Verapamil

Generic Name
Verapamil
Brand Names
Calan, Isoptin, Tarka, Verelan
Drug Type
Small Molecule
Chemical Formula
C27H38N2O4
CAS Number
52-53-9
Unique Ingredient Identifier
CJ0O37KU29
Background

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like diltiazem and flunarizine, bu...

Indication

Verapamil is indicated in the treatment of vasopastic (i.e. Prinzmetal's) angina, unstable angina, and chronic stable angina. It is also indicated to treat hypertension, for the prophylaxis of repetitive paroxysmal supraventricular tachycardia, and in combination with digoxin to control ventricular rate in patients with atrial fibrillation or atrial flutter....

Associated Conditions
Chronic Stable Angina Pectoris, Cluster Headache, Heart Rate, Hypertension, Paroxysmal Supraventricular Tachycardia (PSVT), Supra-ventricular Tachyarrhythmias, Unstable Angina Pectoris, Vasospastic Angina
Associated Therapies
-

Is Verapamil In TransRadial Interventions OmittabLe?

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2011-07-26
Last Posted Date
2014-06-02
Lead Sponsor
State Health Center, Hungary
Target Recruit Count
591
Registration Number
NCT01402427
Locations
🇭🇺

State Health Center, Budapest, Hungary

Comparison of Medical Therapies in Marfan Syndrome.

First Posted Date
2011-02-14
Last Posted Date
2011-02-14
Lead Sponsor
Cardiff University
Target Recruit Count
18
Registration Number
NCT01295047
Locations
🇬🇧

Wales Heart Research Institute, Cardiff University, Cardiff, United Kingdom

DDI Between BI Empagliflozin (10773) and Verapamil

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-01-13
Last Posted Date
2014-06-17
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
16
Registration Number
NCT01276301
Locations
🇩🇪

1245.43.1 Boehringer Ingelheim Investigational Site, Biberach, Germany

Drug-Disease Interaction in Crohn's Disease

Phase 1
Completed
Conditions
First Posted Date
2010-12-16
Last Posted Date
2010-12-16
Lead Sponsor
University of Alberta
Registration Number
NCT01261286
Locations
🇨🇦

University of Alberta Hospital, Edmonton, Alberta, Canada

Evaluation of the Drug-drug Interaction Between FosD and Verapamil When Taken Together in Healthy Volunteers

First Posted Date
2010-09-09
Last Posted Date
2010-11-23
Lead Sponsor
AstraZeneca
Target Recruit Count
15
Registration Number
NCT01197781
Locations
🇺🇸

Recruiting Site, Overland Park, Kansas, United States

Study of Verapamil in Refractory Epilepsy

Not Applicable
Conditions
Interventions
First Posted Date
2010-05-19
Last Posted Date
2010-05-19
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
16
Registration Number
NCT01126307
Locations
🇨🇦

Toronto Western Hospital, Toronto, Ontario, Canada

Cluster Headache Cortivazol Injection (CHCI)

First Posted Date
2008-12-09
Last Posted Date
2012-11-27
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
43
Registration Number
NCT00804895
Locations
🇫🇷

CHU Lariboisière, AP-HP, Centre des Urgences Céphalées (Emergency Headacha Center), Paris, Ile de France, France

Effects of Different Vasodilators on Coronary No-reflow During primAry percuTaneous Coronary intErvention in Patients With Acute Myocardial Infarction

First Posted Date
2008-07-10
Last Posted Date
2012-09-24
Lead Sponsor
Fudan University
Target Recruit Count
102
Registration Number
NCT00712894
Locations
🇨🇳

Zhongshan Hospital Fudan University, Shanghai, Shanghai, China

An Interaction Study of Ketoconazole/Verapamil Versus AZD1305

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-07-01
Last Posted Date
2010-12-03
Lead Sponsor
AstraZeneca
Target Recruit Count
27
Registration Number
NCT00707551
Locations
🇩🇪

Research Site, Berlin, Germany

Combination of Hydroxyurea and Verapamil for Refractory Meningiomas

First Posted Date
2008-06-30
Last Posted Date
2017-04-13
Lead Sponsor
University of Utah
Target Recruit Count
8
Registration Number
NCT00706810
Locations
🇺🇸

Huntsman Cancer Institute, Salt Lake City, Utah, United States

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