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Alendronic acid

Generic Name
Alendronic acid
Brand Names
Adrovance, Binosto, Fosamax, Fosamax Plus D, Fosavance
Drug Type
Small Molecule
Chemical Formula
C4H13NO7P2
CAS Number
66376-36-1
Unique Ingredient Identifier
X1J18R4W8P

Overview

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease. It functions by preventing resorption of bone.

Background

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease. It functions by preventing resorption of bone.

Indication

Alendronic acid is indicated for the treatment and prevention of osteoporosis in men and postmenopausal women, treatment of glucocorticoid-induced osteoporosis, and Paget's disease of bone. However, alendronic acid is not indicated for use in pediatric populations or patients with a creatinine clearance <35mL/min.

Associated Conditions

  • Osteogenesis Imperfecta (OI)
  • Osteoporosis
  • Osteoporosis caused by Glucocorticoid Treatment
  • Paget’s Disease

FDA Approved Products

Alendronate Sodium
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:70 mg in 1 1
Approved: 2022/10/29
NDC:50090-5677
FOSAMAX
Manufacturer:Organon LLC
Route:ORAL
Strength:70 mg in 1 1
Approved: 2021/06/01
NDC:78206-135
Alendronate Sodium
Manufacturer:NorthStar Rx LLC
Route:ORAL
Strength:70 mg in 1 1
Approved: 2023/11/21
NDC:16714-633
Alendronate Sodium
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:35 mg in 1 1
Approved: 2022/10/29
NDC:50090-5474
alendronate sodium
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:70 mg in 1 1
Approved: 2017/12/12
NDC:50090-1095

Singapore Approved Products

LENDOMAX TABLET 70MG
Manufacturer:Intas Pharmaceuticals Ltd
Form:TABLET
Strength:70mg
Online:Yes
Approved: 2014/09/08
Approval:SIN14606P
ALENDRONATE MEVON FILM-COATED TABLET 70 MG
Manufacturer:WEST PHARMA - Produções de Especialidades Farmacêuticas, S.A., ATLANTIC PHARMA - Produções Farmacêuticas, S.A., Farmalabor – Produtos Farmaceuticos, S.A.
Form:TABLET, FILM COATED
Strength:70 mg
Online:Yes
Approved: 2018/01/24
Approval:SIN15412P
ALENDRONATE SANDOZ FILM COATED TABLETS 70MG
Manufacturer:Lek Pharmaceuticals d.d., Lek Pharmaceuticals d.d., Poslovna enota PROIZVODNJA LENDAVA (Primary and secondary packager)
Form:TABLET, FILM COATED
Strength:70mg
Online:Yes
Approved: 2014/08/11
Approval:SIN14582P
Fosamax Plus™ 70mg/2800IU Tablet
Manufacturer:Rovi Pharma Industrial Services S.A., Merck Sharp & Dohme B.V. (Primary and Secondary Packager)
Form:TABLET
Strength:70 mg
Online:Yes
Approved: 2005/10/31
Approval:SIN13152P

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