Telithromycin

Generic Name
Telithromycin
Brand Names
Ketek
Drug Type
Small Molecule
Chemical Formula
C43H65N5O10
CAS Number
191114-48-4
Unique Ingredient Identifier
KI8H7H19WL
Background

Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides. Ketolides have been recently added to the macrolide-lincosamide-streptogramin class of antibiotics. Similar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. Telithromyc...

Indication

临床主要用于敏感菌所致的呼吸道感染，包括社区获得性肺炎、慢性支气管炎、急性上颌窦咽炎及扁桃体炎。

Associated Conditions
Mild community-acquired pneumonia, Moderate Community acquired pneumonia
Associated Therapies
-
Clinical Trials
Related News

Ketek in CAP / AECB in Ambulatory Adult Patients

First Posted Date
2007-10-19
Last Posted Date
2007-11-14
Lead Sponsor
Sanofi
Target Recruit Count
174
Registration Number
NCT00546676

Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients With COPD

Phase 4
Completed
Conditions
Bronchitis, Chronic
First Posted Date
2007-10-02
Last Posted Date
2012-02-17
Lead Sponsor
Sanofi
Target Recruit Count
668
Registration Number
NCT00538148

Telithromycin, Treating Adult Outpatients With Mild to Moderate Community-acquired Pneumonia (CAP) in High Bacterial Resistance Areas

Phase 4
Completed
Conditions
Pneumonia
First Posted Date
2007-10-02
Last Posted Date
2012-02-17
Lead Sponsor
Sanofi
Target Recruit Count
978
Registration Number
NCT00538018

AMS VS MOXI Ketek vs Avelox in AMS

Phase 3
Completed
Conditions
Maxillary Sinusitis
First Posted Date
2007-10-01
Last Posted Date
2012-02-17
Lead Sponsor
Sanofi
Target Recruit Count
351
Registration Number
NCT00537563
Locations
🇺🇸

Sanofi-Aventis, Bridgewater, New Jersey, United States

Controlled Trial: 5-day Course of Telithromycin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus

Phase 3
Completed
Conditions
Scrub Typhus
First Posted Date
2006-07-12
Last Posted Date
2019-02-08
Lead Sponsor
Dong-Min Kim
Target Recruit Count
92
Registration Number
NCT00351182
Locations
🇰🇷

Chosun University Hospital, Gwangju, Jeonnam, Korea, Republic of

Intrapulmonary Pharmacokinetics of Antibiotics

Phase 4
Terminated
Conditions
Healthy
First Posted Date
2006-04-18
Last Posted Date
2009-02-13
Lead Sponsor
University of Illinois at Chicago
Target Recruit Count
35
Registration Number
NCT00315601
Locations
🇺🇸

Pulmonary Associates PA, Phoenix, Arizona, United States

TELI TAD - Telithromycin in Tonsillitis in Adolescents and Adults

Phase 3
Terminated
Conditions
Tonsillitis
Pharyngitis
First Posted Date
2006-04-18
Last Posted Date
2009-04-03
Lead Sponsor
Sanofi
Target Recruit Count
233
Registration Number
NCT00315549
Locations
🇨🇷

Sanofi-Aventis, San Jose, Costa Rica

TELI COM - Telithromycin in Children With Otitis Media

First Posted Date
2006-04-17
Last Posted Date
2009-04-03
Lead Sponsor
Sanofi
Target Recruit Count
1500
Registration Number
NCT00315003
Locations
🇵🇪

Sanofi-Aventis, Lima, Peru

Telithromycin in Acute Exacerbation of Chronic Bronchitis

Phase 4
Terminated
Conditions
Bronchitis, Chronic
Interventions
Drug: Telithromycin
First Posted Date
2006-02-07
Last Posted Date
2009-12-09
Lead Sponsor
Sanofi
Target Recruit Count
54
Registration Number
NCT00288223
Locations
🇹🇷

Sanofi-Aventis, Istanbul, Turkey

TELICAST : Telithromycin in Acute Exacerbations of Asthma

Phase 3
Completed
Conditions
Asthma
First Posted Date
2006-01-09
Last Posted Date
2009-09-15
Lead Sponsor
Sanofi
Registration Number
NCT00273520
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