Overview
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Background
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Indication
Interferon beta-1b is a drug used for the treatment of relapsing/remitting multiple sclerosis. It has been shown to slow the advance of the disease as well as to decrease the frequency of attacks.
Associated Conditions
- Relapsing Multiple Sclerosis (RMS)
- Secondary Progressive Multiple Sclerosis (SPMS)
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2023/09/26 | N/A | Active, not recruiting | |||
2020/12/01 | Phase 2 | UNKNOWN | |||
2020/07/31 | Phase 2 | UNKNOWN | |||
2020/07/10 | Phase 2 | UNKNOWN | |||
2020/04/22 | N/A | Completed | |||
2020/04/17 | Phase 2 | Completed | |||
2020/04/13 | Phase 2 | Completed | |||
2020/02/19 | Phase 2 | Completed | |||
2018/01/23 | N/A | Completed | |||
2017/06/06 | Phase 4 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
Withdrawn | 5/20/2008 | ||
Authorised | 11/30/1995 | ||
Authorised | 11/30/1995 | ||
Withdrawn | 5/20/2008 |
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| BETAFERON interferon beta-1b rbe 0.25mg (8 million IU) powder for injection vial with diluent syringe | 83309 | Medicine | A | 8/9/2002 |