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Interferon beta-1b

Generic Name
Interferon beta-1b
Brand Names
Betaferon, Betaseron, Extavia
Drug Type
Biotech
Chemical Formula
-
CAS Number
145155-23-3
Unique Ingredient Identifier
TTD90R31WZ
Background

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD

Indication

Interferon beta-1b is a drug used for the treatment of relapsing/remitting multiple sclerosis. It has been shown to slow the advance of the disease as well as to decrease the frequency of attacks.

Associated Conditions
Relapsing Multiple Sclerosis (RMS), Secondary Progressive Multiple Sclerosis (SPMS)
Associated Therapies
-

Open Label Phase I Study To Evaluate the Safety of Combination Therapy With AZT and Interferon-Beta in Patients With AIDS Related Kaposi's Sarcoma

Phase 1
Completed
Conditions
HIV Infections
Sarcoma, Kaposi
First Posted Date
2001-08-31
Last Posted Date
2021-11-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
36
Registration Number
NCT00000695
Locations
🇺🇸

Los Angeles County - USC Med Ctr, Los Angeles, California, United States

🇺🇸

UCLA CARE Ctr, Los Angeles, California, United States

🇺🇸

Northwestern Univ Med School, Chicago, Illinois, United States

and more 1 locations
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