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Neostigmine

Generic Name
Neostigmine
Brand Names
Bloxiverz, Prevduo, Prostigmin
Drug Type
Small Molecule
Chemical Formula
C12H19N2O2
CAS Number
59-99-4
Unique Ingredient Identifier
3982TWQ96G

Overview

A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.

Background

A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.

Indication

Neostigmine is used for the symptomatic treatment of myasthenia gravis by improving muscle tone.

Associated Conditions

  • Curarization therapy
  • Myasthenia Gravis
  • Neuromuscular Blockade
  • Postoperative Urinary Retention (POUR)
  • Acute Colonic Pseudo-Obstruction
  • Post-operative intestinal atony

FDA Approved Products

PREVDUO
Manufacturer:PAR PHARMACEUTICAL, INC.
Route:INTRAVENOUS
Strength:1 mg in 1 mL
Approved: 2023/05/11
NDC:42023-269
neostigmine methylsulfate
Manufacturer:Camber Pharmaceuticals Inc.
Route:INTRAVENOUS
Strength:1 mg in 1 mL
Approved: 2021/02/10
NDC:31722-995
NEOSTIGMINE METHYLSULFATE
Manufacturer:Medical Purchasing Solutions, LLC
Route:INTRAVENOUS
Strength:1 mg in 1 mL
Approved: 2024/03/05
NDC:71872-7322
Neostigmine Methylsulfate
Manufacturer:Somerset Therapeutics, LLC
Route:INTRAVENOUS
Strength:1 mg in 1 mL
Approved: 2021/07/27
NDC:70069-806
Neostigmine Methylsulfate
Manufacturer:Somerset Therapeutics, LLC
Route:INTRAVENOUS
Strength:0.5 mg in 1 mL
Approved: 2021/07/27
NDC:70069-805

Singapore Approved Products

No Singapore products found for this drug

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