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Sodium fluoride

Generic Name
Sodium fluoride
Brand Names
60 Second Taste, Clinpro 5000, Ctx4 Gel, Denta 5000 Plus, Denticare Denti Foam, Denticare Neutral, Denticare Pro Gel, Fluorishield, Fluoritab, Flura-drops, Gelato Sodium Fluoride, Kolorz, Ludent, Meijer, Mvc-fluoride, Neutracare, Neutramaxx, Oral-B Minute-foam, Oral-B Neutra, Pcxx Neutral Foam, Pcxx Neutral Rinse, Perfect Choice One Minute, Prevident, Prevident 5000 Sensitive, Prevident Dental Rinse, Prodenrx Rinse, Zooby Fluoride Foam
Drug Type
Small Molecule
Chemical Formula
FNa
CAS Number
7681-49-4
Unique Ingredient Identifier
8ZYQ1474W7
Background

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated drinking water showed less tooth decay than those without fluoridated water. The use of fluoride in dental practice began in the 1940s. Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride treatments provided in dental care. According to the American Dental Association (ADA), thorough evidence reviews have indicated that the use of fluoride to prevent and control dental caries is safe when used correctly and is highly effective in reducing the prevalence of caries.

Indication

Sodium fluoride in the oral or topical form is indicated for the prevention and control of dental caries and for the maintenance of dental health. Fluoride supplements in the form of tablets and other formulas may be prescribed to prevent tooth decay in high-risk children aged 6 months to 16 years old whose drinking water source contains low fluoride concentrations.

Associated Conditions
Cavity, Dental Cavity, Dental Decay, Dental Health, Enamel Caries, Partial Denture Wearers Wear of the Natural Enamel, Sensitivity, Tooth, Trace Element Deficiency, Wear of the Natural Enamel caused by teeth grinding
Associated Therapies
Parenteral Nutrition

Utah Becomes First State to Ban Fluoride in Public Water Systems

• Utah has made history as the first U.S. state to ban community water fluoridation after Governor Spencer Cox signed legislation that will take effect on May 7, 2025. • The controversial ban comes amid debates over fluoride's safety, with supporters citing individual choice while dental experts warn it could increase cavity rates, especially in low-income communities. • Research indicates fluoridation reduces cavities by approximately 27-30% in adults and children, raising concerns that the ban may lead to worsening oral health outcomes across the state.

Novavax's Updated COVID-19 Vaccine Now Available at Major U.S. Pharmacies

• Novavax's 2024-2025 formula COVID-19 vaccine (NVX-CoV2705) is now stocked at major pharmacies across the U.S. for individuals aged 12 and older. • The updated vaccine targets the JN.1 variant and has demonstrated cross-reactivity against JN.1 lineage viruses, offering a protein-based alternative. • Novavax has more than doubled the number of locations stocking its vaccine compared to last year, with a more convenient pre-filled syringe presentation. • The vaccine has received Emergency Use Authorization from the FDA and is available at locations including CVS, Walgreens, Rite Aid and Costco.
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