Drometrizole trisiloxane
- Generic Name
- Drometrizole trisiloxane
- Drug Type
- Small Molecule
- Chemical Formula
- C24H39N3O3Si3
- CAS Number
- 155633-54-8
- Unique Ingredient Identifier
- HC22845I1X
Overview
Drometrizole trisiloxane is a photostable UVA and UVB light filter . The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and Japan, among other countries. Despite being used elsewhere in the world with relatively few reports of adverse reactions, the FDA continues to cite that the existing scientific record is not sufficient to establish the compound as being generally recognized as safe and effective for over-the-counter sunscreen use .
Background
Drometrizole trisiloxane is a photostable UVA and UVB light filter . The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and Japan, among other countries. Despite being used elsewhere in the world with relatively few reports of adverse reactions, the FDA continues to cite that the existing scientific record is not sufficient to establish the compound as being generally recognized as safe and effective for over-the-counter sunscreen use .
Indication
Drometrizole trisiloxane is used as an active ingredient in various sunscreens for the indication of protecting the skin by absorbing the damaging UV radiation of sunlight .
Associated Conditions
- Sunburn
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
|---|---|---|---|---|---|
TOPICAL | 5 mg in 1 mL | 2023/12/31 | 49967-704 | ||
TOPICAL | 5 mg in 1 mL | 2023/12/31 | 49967-083 |
EMA Approved Products
Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
|---|
No EMA products found
No EMA products found for this drug
HSA Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. |
|---|
No HSA products found
No HSA products found for this drug
NMPA Approved Products
Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
|---|
No NMPA products found
No NMPA products found for this drug
PPB Approved Products
Product Name | Registration Code | Company | Category | Sale Type | Reg. Date |
|---|
No PPB products found
No PPB products found for this drug
TGA Approved Products
Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
|---|---|---|---|---|---|
297587 | Active | 2017/12/15 | drometrizole trisiloxane | ||
308621 | Active | 2018/08/24 | drometrizole trisiloxane | ||
300899 | Active | 2018/03/16 | drometrizole trisiloxane | ||
300600 | Active | 2018/03/09 | drometrizole trisiloxane | ||
404334 | Active | 2023/02/03 | drometrizole trisiloxane | ||
307005 | Active | 2018/07/13 | drometrizole trisiloxane | ||
297590 | Active | 2017/12/15 | drometrizole trisiloxane | ||
315642 | Active | 2019/03/22 | drometrizole trisiloxane | ||
294062 | Active | 2017/09/19 | drometrizole trisiloxane | ||
307004 | Active | 2018/07/13 | drometrizole trisiloxane |