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Pirenzepine

Generic Name
Pirenzepine
Drug Type
Small Molecule
Chemical Formula
C19H21N5O2
CAS Number
28797-61-7
Unique Ingredient Identifier
3G0285N20N
Background

An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients.

Indication

For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer.

Associated Conditions
Gastric Ulcer, Small intestine ulcer

A 16-Week Study of Pirenzepine or Placebo to Treat HIV-Associated Distal Sensory Polyneuropathy in Patients With HIV

Phase 2
Completed
Conditions
HIV Associated Polyneuropathy
Interventions
Drug: Placebo
First Posted Date
2021-08-13
Last Posted Date
2023-12-04
Lead Sponsor
WinSanTor, Inc
Target Recruit Count
16
Registration Number
NCT05005078
Locations
🇺🇸

University of California San Diego, San Diego, California, United States

🇺🇸

Palmtree Clinical Research, Palm Springs, California, United States

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