MedPath

Avanafil

Generic Name
Avanafil
Brand Names
Spedra, Stendra
Drug Type
Small Molecule
Chemical Formula
C23H26ClN7O3
CAS Number
330784-47-9
Unique Ingredient Identifier
DR5S136IVO
Background

Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with off-target PDE6 inhibition.

It first received FDA approval on April 27, 2012, with subsequent EMA approval in June 2013.

Indication

Avanafil is indicated for the treatment of erectile dysfunction.

Associated Conditions
Erectile Dysfunction
Associated Therapies
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Proprietary Technology Addressing the Rx-to-OTC Switch Self-Care Market Valued at over $38 Billion annually

Petros Pharmaceuticals shifts strategy to develop a proprietary SaaS and SaMD platform for Rx-to-OTC drug switches, leveraging AI and quantum computing. This aims to expand consumer access to medications, targeting the $38 billion self-care market. The company's technology could facilitate FDA-approved OTC switches, enhancing commercial opportunities.
stocktitan.net
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Petros Pharmaceuticals Pivots to $38B Self-Care Market

Petros Pharmaceuticals shifts focus to develop a proprietary SaaS and SaMD platform for Rx-to-OTC switches, aiming to tap into the $38 billion self-care market. Leveraging AI and quantum computing, the technology seeks to facilitate OTC transitions for various drugs, aligning with FDA and HHS policies for expanded medication access.
aol.com
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Intimacy After 70: How to Keep Things Lively in the Bedroom as a Senior

The article discusses the intimate lives of older people, emphasizing that age does not limit sexual activity. It highlights potential challenges like erectile dysfunction and decreased libido but also the benefits of maintaining an active intimate life, including improved health and social life. Tips for seniors include regular health check-ups, maintaining an active lifestyle, considering ED medication, and practicing safe sex. The article also touches on the importance of communication with partners and adapting to changes together.
biospace.com
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Petros Pharmaceuticals Successfully Launches AI Tool In Human Factors Study for STENDRA

Petros Pharmaceuticals integrates AI into a Human Factors Study for STENDRA (avanafil), aiming for OTC status. The AI tool, developed with a software developer, assesses safe drug administration. The study, following FDA guidance, evaluates the web app's effectiveness for patient self-screening, supporting STENDRA's potential as the first OTC erectile dysfunction medication.
drug-dev.com
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Petros Pharmaceuticals Successfully Launches AI Tool for STENDRA's OTC Availability

Petros Pharmaceuticals launched an AI tool in collaboration with a major software provider, integrating it into a web app for patient self-screening. This tool aims to optimize STENDRA's OTC availability, addressing FDA requests for safe drug administration. A Human Factors Study assesses the web app's safety and effectiveness, supporting Petros' goal to make STENDRA the first OTC erectile dysfunction medication.
biospace.com
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Petros Pharmaceuticals Enters into AI Licensing to Facilitate STENDRA's Transition to Over-the-Counter Status

Petros Pharmaceuticals partners with an AI software provider to facilitate STENDRA's transition to over-the-counter status, aiming to enhance self-screening for erectile dysfunction treatment. This initiative aligns with FDA and ACNU guidelines, leveraging AI for safe, appropriate consumer access.
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