Hyaluronic acid
- Generic Name
- Hyaluronic acid
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C28H44N2O23
- CAS Number
- 9004-61-9
- Unique Ingredient Identifier
- S270N0TRQY
- Background
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not limited to woun...
- Indication
The intra-articular preparations of hyaluronic acid are indicated for knee pain associated with osteoarthritis. Hyaluronic acid is used in cosmetic applications to prevent and reduce the appearance of wrinkles on the face, and as a dermal filler to correct facial imperfections or other imperfections on other parts of the body. It is frequently an ingredient ...
- Associated Conditions
- Actinic Keratosis (AK), Burns, Chronic Skin Ulcers, Conjunctivitis, Dehydration, Dermabrasion, Dermatosis, Dry Eyes, Facial Defect, Interstitial Cystitis, Keratoconjunctivitis, Ocular Irritation, Osteoarthritis (OA), Pain of the knee, Seasonal Allergic Conjunctivitis, Skin Burn, Skin Irritation, Skin fissures, Tissue Adhesions, Varicose Ulcers, Wound, Eye discomfort, Facial fine wrinkling, Sensation of burning in the eyes, Superficial Wounds
- Associated Therapies
- Dermal Filler, Promotion of wound healing, Synovial Fluid Lubrication
Transcutaneous Pulsed Radiofrequency Application Plus Genicular Nerve Block Versus Intraarticular Hyaluronic Acid Injection for Management of Chronic Pain in Knee Osteoarthritis.
- Conditions
- Interventions
- First Posted Date
- 2024-11-29
- Last Posted Date
- 2024-11-29
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 80
- Registration Number
- NCT06710782
- Locations
- 🇪🇬
Tanta University, Tanta, ElGharbia, Egypt
EffIcacy Between Arthrocentesis With High Versus Low Molecular Weight Hyaluronic Acid in Treatment of TMJ Disorders
- Conditions
- Interventions
- First Posted Date
- 2024-11-19
- Last Posted Date
- 2024-11-19
- Lead Sponsor
- Basel khaled mohamed
- Target Recruit Count
- 30
- Registration Number
- NCT06694532
- Locations
- 🇪🇬
Assiut Univeristy, Assiut, Egypt
The Role of Butirprost® in Combination With Antibiotics in Chronic Bacterial Prostatitis (CBP) Treatment
- Conditions
- Interventions
- First Posted Date
- 2024-11-12
- Last Posted Date
- 2024-11-18
- Lead Sponsor
- Federico II University
- Target Recruit Count
- 60
- Registration Number
- NCT06684626
- Locations
- 🇮🇹
University of Naples Federico II, Napoli, Italy
Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis
- Conditions
- Interventions
- First Posted Date
- 2024-06-21
- Last Posted Date
- 2024-12-06
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 42
- Registration Number
- NCT06469216
- Locations
- 🇪🇬
Al-Ahrar teaching hospital, Zagazig, Sharqia, Egypt
🇪🇬Ahmed Maher teaching hospitals, Cairo, Egypt
Hyaluronic Acid Injection in the Glans Penis Versus Selective Serotonin Reuptake Inhibitors for Lifelong Premature
- Conditions
- Interventions
- First Posted Date
- 2024-06-11
- Last Posted Date
- 2024-06-13
- Lead Sponsor
- New Valley University
- Target Recruit Count
- 60
- Registration Number
- NCT06451406
- Locations
- 🇪🇬
New Valley University, New Valley, Egypt
Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss
- Conditions
- Interventions
- First Posted Date
- 2024-05-31
- Last Posted Date
- 2024-06-05
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 26
- Registration Number
- NCT06437054
Chitosan-Hyaluronate Gel Mixture Vs Hyaluronic for Internal Derangement
- Conditions
- Interventions
- First Posted Date
- 2024-05-23
- Last Posted Date
- 2024-05-23
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 20
- Registration Number
- NCT06426199
- Locations
- 🇪🇬
Suez University, Suez, Egypt
Clinical and Immunological Evaluation of HA in Treatment of Periodontitis
- Conditions
- Interventions
- First Posted Date
- 2024-03-22
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Sana'a University
- Target Recruit Count
- 24
- Registration Number
- NCT06324474
- Locations
- 🇾🇪
Sana'a university, Sana'a, Yemen
Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis
- First Posted Date
- 2024-02-28
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Phramongkutklao College of Medicine and Hospital
- Target Recruit Count
- 176
- Registration Number
- NCT06279507
- Locations
- 🇹🇭
Phramongkutklao Hospital, Bangkok, Thailand
Randomized, Controlled, Multicenter Study of Extracellular Vesicles From Human Adipose Tissue Promoting Wound Healing
- Conditions
- Interventions
- First Posted Date
- 2024-02-12
- Last Posted Date
- 2024-02-12
- Target Recruit Count
- 20
- Registration Number
- NCT06253975
- Locations
- 🇨🇳
Shanghai 9th People's Hospital, Shanghai, Shanghai, China
Drug Development Updates
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