Alprostadil
- Generic Name
- Alprostadil
- Brand Names
- Caverject, Edex, Muse, Prostin Vr
- Drug Type
- Small Molecule
- Chemical Formula
- C20H34O5
- CAS Number
- 745-65-3
- Unique Ingredient Identifier
- F5TD010360
- Background
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment is either...
- Indication
Alprostadil is indicated for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. It is also indicated for the treatment of erectile dysfunction due to neurogenic...
- Associated Conditions
- Erectile Dysfunction, Patent Ductus Arteriosus (PDA), Raynaud's Phenomenon
- Associated Therapies
- -
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