Chlorhexidine

Brand Names: Betasept, Hibiclens, Instillagel, Nupro Chlorhexidine, Oris, Oro-Clense, Paroex, Perichlor, Peridex, Periochip, Periogard, Prevora, X-pur

Background: Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings a...

Indication: Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures. Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis and a slow-release "chip" which is inserted into periodo...

Associated Conditions: Aphthous ulcer, Catarrh of the throat, Chemotherapy Induced Oral Mucositis, Chronic Wounds, Decubitus Ulcer, Dental Cavity, Dysphagia, Eczema infected, Foeter Ex Ore, Gingival Bleeding, Gingival Diseases, Gingivitis, Glossitis, Hoarseness, Infection, Infectious Periodontal Diseases, Injury Throat, Mild to Moderate Inflammatory Reaction of the Oral Cavity, Mild to Moderate Inflammatory Reaction of the Pharynx, Mouth injury, Mucositis, Neurodermatitis, Ocular Inflammation, Ocular Irritation, Oral Aphthous Ulcer, Pain, Periodontitis, Pharyngitis, Plaque, Dental, Postoperative Wound Infection, Purulent Gingivitis, Radiation Mucositis, Red eye, Ringworm, Skin Infections, Sore Throat, Stomatitis, Surgical Wounds, Tissue Damage, Tonsillitis, Ulcers, Leg, Wound Infections, Bacterial skin infections, Dry, cracked skin, Gum pain, Moderate Gingivitis, Oral infections, Oral lesions, Recurrent Oral fungal infection, Severe Gingivitis, Superficial Wounds, Throat disinfection, Tongue inflammation

Associated Therapies: Anesthesia of Mucous Membrane, Antimicrobial Therapy, Contact Lens Care, Disinfection, Disinfection of External Genitalia, Disinfection of the Urethra, Disinfection of the Vaginal Mucosa, Irrigation therapy, Lubrication of the Urethra, Oral Care, Oral Hygiene, Oropharyngeal antisepsis, Promotion of wound healing, Skin disinfection, Surgical Scrubbing, Topical Antisepsis, Urethral Anesthesia, Wound Cleansing, Oral antisepsis, Oral disinfection

Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar

Phase 4

Completed

Phase 3

Recruiting

Interventions: Other: Saline
Other: Povidone-Iodine
Drug: Vancomycin Hydrochloride
Drug: Chlorhexidine Gluconate

Locations: 🇨🇦
Hamilton Health Sciences - Juravinski Hospital and Cancer Centre, Hamilton, Ontario, Canada

Phase 2

Recruiting

Interventions: Drug: Amivantamab
Drug: Lazertinib
Drug: Doxycycline
Drug: Minocycline
Drug: Clindamycin
Drug: Chlorhexidine
Other: Noncomedogenic skin moisturizer

Locations: 🇺🇸
USC Norris Oncology Hematology Newport Beach, Newport Beach, California, United States
🇺🇸
Kaiser Permanente Oakland Medical Center, Oakland, California, United States
🇺🇸
Kaiser Permanente Roseville Medical Center, Roseville, California, United States