Chlorhexidine

Generic Name
Chlorhexidine
Brand Names
Betasept, Hibiclens, Instillagel, Nupro Chlorhexidine, Oris, Oro-Clense, Paroex, Perichlor, Peridex, Periochip, Periogard, Prevora, X-pur
Drug Type
Small Molecule
Chemical Formula
C22H30Cl2N10
CAS Number
55-56-1
Unique Ingredient Identifier
R4KO0DY52L
Background

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings a...

Indication

Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures. Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis and a slow-release "chip" which is inserted into periodo...

Associated Conditions
Aphthous ulcer, Catarrh of the throat, Chemotherapy Induced Oral Mucositis, Chronic Wounds, Decubitus Ulcer, Dental Cavity, Dysphagia, Eczema infected, Foeter Ex Ore, Gingival Bleeding, Gingival Diseases, Gingivitis, Glossitis, Hoarseness, Infection, Infectious Periodontal Diseases, Injury Throat, Mild to Moderate Inflammatory Reaction of the Oral Cavity, Mild to Moderate Inflammatory Reaction of the Pharynx, Mouth injury, Mucositis, Neurodermatitis, Ocular Inflammation, Ocular Irritation, Oral Aphthous Ulcer, Pain, Periodontitis, Pharyngitis, Plaque, Dental, Postoperative Wound Infection, Purulent Gingivitis, Radiation Mucositis, Red eye, Ringworm, Skin Infections, Sore Throat, Stomatitis, Surgical Wounds, Tissue Damage, Tonsillitis, Ulcers, Leg, Wound Infections, Bacterial skin infections, Dry, cracked skin, Gum pain, Moderate Gingivitis, Oral infections, Oral lesions, Recurrent Oral fungal infection, Severe Gingivitis, Superficial Wounds, Throat disinfection, Tongue inflammation
Associated Therapies
Anesthesia of Mucous Membrane, Antimicrobial Therapy, Contact Lens Care, Disinfection, Disinfection of External Genitalia, Disinfection of the Urethra, Disinfection of the Vaginal Mucosa, Irrigation therapy, Lubrication of the Urethra, Oral Care, Oral Hygiene, Oropharyngeal antisepsis, Promotion of wound healing, Skin disinfection, Surgical Scrubbing, Topical Antisepsis, Urethral Anesthesia, Wound Cleansing, Oral antisepsis, Oral disinfection
Clinical Trials
Related News

Chlorhexidine Versus Povidone-Iodine Antisepsis for Reduction of Post Cesarean Section Surgical Site Infection

First Posted Date
2015-03-24
Last Posted Date
2015-03-24
Lead Sponsor
Ain Shams Maternity Hospital
Target Recruit Count
410
Registration Number
NCT02396329
Locations
🇪🇬

Ain Shams Maternity Hospital, Cairo, Egypt

Nitrous Oxide for Pain Management of Intrauterine Device (IUD) Insertion

First Posted Date
2015-03-18
Last Posted Date
2016-02-03
Lead Sponsor
University of New Mexico
Target Recruit Count
80
Registration Number
NCT02391714
Locations
🇺🇸

Center for Reproductive Health, Albuquerque, New Mexico, United States

Antimicrobial Activity of Two Mouthwashes

First Posted Date
2015-03-02
Last Posted Date
2017-01-10
Lead Sponsor
Universidade do Vale do Sapucai
Target Recruit Count
30
Registration Number
NCT02375178

Antimicrobial Photodynamic Therapy Applied in Orthodontic. Orthodontic Patients.

First Posted Date
2015-01-13
Last Posted Date
2015-01-13
Lead Sponsor
University of Sao Paulo
Target Recruit Count
24
Registration Number
NCT02337192
Locations
🇧🇷

Vitor Hugo Panhóca, São Carlos, SP, Brazil

Pilot Study: Safety of Chlorhexidine (CHG) Baths in Patients Less Than 2 Months of Age

First Posted Date
2014-12-29
Last Posted Date
2021-07-27
Lead Sponsor
Celeste Chandonnet
Target Recruit Count
10
Registration Number
NCT02326467
Locations
🇺🇸

Boston Children's Hospital, Boston, Massachusetts, United States

Preoperative CHG Cloth on Healthy Subjects

First Posted Date
2014-11-14
Last Posted Date
2021-04-30
Lead Sponsor
Medline Industries
Target Recruit Count
879
Registration Number
NCT02291601
Locations
🇺🇸

BioScience, Butte, Montana, United States

Neonatal Package Study in Rural District of Pakistan

First Posted Date
2014-10-31
Last Posted Date
2016-06-09
Lead Sponsor
Aga Khan University
Target Recruit Count
1450
Registration Number
NCT02279381
Locations
🇵🇰

Taluka Hospital KN Shah, Dadu, Sindh, Pakistan

The Effect of Chlorhexidine on the Oral and Lung Microbiota in Chronic Obstructive Pulmonary Disease

First Posted Date
2014-09-30
Last Posted Date
2020-12-29
Lead Sponsor
University of Minnesota
Target Recruit Count
44
Registration Number
NCT02252588
Locations
🇺🇸

VA Medical Center, Minneapolis, Minnesota, United States

Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Subjects

First Posted Date
2014-08-22
Last Posted Date
2021-05-21
Lead Sponsor
Medline Industries
Target Recruit Count
347
Registration Number
NCT02222896
Locations
🇺🇸

MBT, Sterling, Virginia, United States

Checklist to Prevent MRSA Surgical Site Infections

First Posted Date
2014-08-13
Last Posted Date
2021-03-11
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
1794
Registration Number
NCT02216227
Locations
🇺🇸

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland, United States

🇺🇸

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts, United States

🇺🇸

VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan, United States

and more 8 locations
© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy