Amiodarone
- Generic Name
- Amiodarone
- Brand Names
- Nexterone, Pacerone
- Drug Type
- Small Molecule
- Chemical Formula
- C25H29I2NO3
- CAS Number
- 1951-25-3
- Unique Ingredient Identifier
- N3RQ532IUT
- Background
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone use s...
- Indication
The FDA approved indications for amiodarone are recurrent ventricular fibrillation (VF) and recurrent hemodynamically unstable ventricular tachycardia (VT). The FDA emphasizes that this drug should only be given in these conditions when they are clinically documented and have not responded to normal therapeutic doses of other antiarrhythmic agents, or when o...
- Associated Conditions
- Atrial Fibrillation, Supraventricular Tachycardia (SVT), Recurrent Ventricular fibrillation, Recurrent hemodynamically unstable Ventricular tachycardia
- Associated Therapies
- -
Treatment of Postoperative Atrial Fibrillation - Comparison of Amiodarone and Placebo.
- First Posted Date
- 2016-03-22
- Last Posted Date
- 2016-03-22
- Lead Sponsor
- Rambam Health Care Campus
- Target Recruit Count
- 400
- Registration Number
- NCT02715687
Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic Shock
- Conditions
- Interventions
- First Posted Date
- 2016-01-29
- Last Posted Date
- 2019-04-02
- Target Recruit Count
- 9
- Registration Number
- NCT02668432
- Locations
- 🇺🇸
University Hospital, San Antonio, Texas, United States
AMIOdarone vs. Catheter Ablation for Prevention of Recurrent Symptomatic Atrial Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2015-01-19
- Last Posted Date
- 2021-02-09
- Lead Sponsor
- Population Health Research Institute
- Target Recruit Count
- 10
- Registration Number
- NCT02341105
- Locations
- 🇨🇦
Hamilton Health Sciences, Hamilton, Ontario, Canada
INTERVENE: Indian Trial of Endocardial Ventricular Substrate Ablation to Prevent Recurrent VT Events
- Conditions
- Interventions
- First Posted Date
- 2014-11-25
- Last Posted Date
- 2020-01-27
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 53
- Registration Number
- NCT02301390
- Locations
- 🇮🇳
CARE Institute of Medical Science, Ahmedabad, India
🇮🇳CARE Hospital, Hyderabad, India
🇮🇳Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India
Catheter Ablation Compared With Pharmacological Therapy for Atrial Fibrillation (CAPTAF Trial)
- First Posted Date
- 2014-11-19
- Last Posted Date
- 2017-05-09
- Lead Sponsor
- Uppsala University Hospital
- Target Recruit Count
- 152
- Registration Number
- NCT02294955
- Locations
- 🇸🇪
Carina Blomström Lundqvist, Uppsala, Sweden
Bioavailability of Dabigatran and Amiodarone After Multiple Oral Administrations of Dabigatran Etexilate With or Without Amiodarone as Single Dose in Healthy Male and Female Volunteers
- First Posted Date
- 2014-06-23
- Last Posted Date
- 2014-06-23
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 24
- Registration Number
- NCT02171026
Antiarrhythmic Drugs Assessment in Preventing Atrial Fibrillation
- First Posted Date
- 2014-05-23
- Last Posted Date
- 2014-05-23
- Target Recruit Count
- 600
- Registration Number
- NCT02145546
- Locations
- 🇨🇳
Xinhua Hospital, Shanghai Jiao Tong University School of Medicne, Shanghai, Shanghai, China
Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2014-05-07
- Last Posted Date
- 2019-03-15
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 523
- Registration Number
- NCT02132767
- Locations
- 🇺🇸
Montefiore Einstein Heart Center, Bronx, New York, United States
🇺🇸Icahn School of Medicine at Mount Sinai, New York, New York, United States
🇺🇸Columbia University Medical Center, New York, New York, United States
Cardiac Resynchronization in Atrial Fibrillation Trial - a Pilot Study
- First Posted Date
- 2013-05-09
- Last Posted Date
- 2015-03-10
- Lead Sponsor
- National Institute of Cardiology, Warsaw, Poland
- Target Recruit Count
- 60
- Registration Number
- NCT01850277
- Locations
- 🇵🇱
Institute of Cardiology, II Dept. of Coronary Heart Disease, Warsaw, Poland
Safety and Efficacy of Oral Versus Intravenous Amiodarone in the Treatment of AF
- First Posted Date
- 2013-03-25
- Last Posted Date
- 2013-03-25
- Lead Sponsor
- Western Galilee Hospital-Nahariya
- Target Recruit Count
- 104
- Registration Number
- NCT01817439
- Locations
- 🇮🇱
Western Galilee Hospital, Naharia, Israel
Drug Development Updates
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