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Cefacetrile is a broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections.
Cefacetrile is a broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections.
In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
Cefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
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