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Daunorubicin

Generic Name
Daunorubicin
Brand Names
Cerubidine, Vyxeos
Drug Type
Small Molecule
Chemical Formula
C27H29NO10
CAS Number
20830-81-3
Unique Ingredient Identifier
ZS7284E0ZP

Overview

A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.

Background

A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.

Indication

For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults. Daunorubicin is indicated in combination with cytarabine for the treatment of newly-diagnosed therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (AML-MRC) in adults and pediatric patients 1 year and older.

Associated Conditions

  • Acute Lymphoblastic Leukaemias (ALL)
  • Acute Myeloid Leukemia With Myelodysplasia-Related Changes
  • Chronic Phase Chronic Myeloid Leukemia
  • Ewing's Sarcoma
  • Lymphoma, Diffuse
  • Myeloblastic Leukemia
  • Non-Hodgkin's Lymphoma (NHL)
  • Treatment-Related Acute Myeloid Leukemia
  • Wilms' tumor

FDA Approved Products

Daunorubicin Hydrochloride
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:INTRAVENOUS
Strength:5 mg in 1 mL
Approved: 2024/02/15
NDC:0143-9551
Daunorubicin Hydrochloride
Manufacturer:Hisun Pharmaceuticals USA, Inc.
Route:INTRAVENOUS
Strength:5 mg in 1 mL
Approved: 2023/01/01
NDC:42658-021
Daunorubicin Hydrochloride
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:INTRAVENOUS
Strength:5 mg in 1 mL
Approved: 2024/02/15
NDC:0143-9550
Daunorubicin Hydrochloride
Manufacturer:Hisun Pharmaceuticals USA, Inc.
Route:INTRAVENOUS
Strength:5 mg in 1 mL
Approved: 2021/02/09
NDC:42658-019
Daunorubicin Hydrochloride
Manufacturer:Hisun Pharmaceuticals USA, Inc.
Route:INTRAVENOUS
Strength:5 mg in 1 mL
Approved: 2021/02/09
NDC:42658-021

Singapore Approved Products

DAUNOCIN FOR INJECTION 20 mg/vial
Manufacturer:KOREA UNITED PHARMACEUTICAL INC
Form:INJECTION, POWDER, FOR SOLUTION
Strength:20 mg/vial
Online:Yes
Approved: 1999/06/29
Approval:SIN11002P

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