Esmolol
- Generic Name
- Esmolol
- Brand Names
- Brevibloc
- Drug Type
- Small Molecule
- Chemical Formula
- C16H25NO4
- CAS Number
- 81147-92-4
- Unique Ingredient Identifier
- MDY902UXSR
- Background
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decrea...
- Indication
For the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention.
- Associated Conditions
- Hypertension, Tachycardia, Abnormal ventricular rate, Heart rate abnormal
- Associated Therapies
- -
Esmolol Infusion in Patients Undergoing Craniotomy
- Conditions
- Interventions
- First Posted Date
- 2015-05-27
- Last Posted Date
- 2015-07-08
- Lead Sponsor
- George Papanicolaou Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT02455440
- Locations
- 🇬🇷
George Papanikolaou General Hospital, Thessaloniki, Greece
Esmolol to Treat the Hemodynamic Effects of Septic Shock
- Conditions
- Interventions
- First Posted Date
- 2015-02-24
- Last Posted Date
- 2021-06-28
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT02369900
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy
- First Posted Date
- 2014-12-31
- Last Posted Date
- 2018-11-30
- Lead Sponsor
- B.P. Koirala Institute of Health Sciences
- Target Recruit Count
- 90
- Registration Number
- NCT02327923
- Locations
- 🇳🇵
BP Koirala Institute of Health Sciences, Dharan, Sunsari District, Nepal
Echocardiographic and Arterial Pressure Waveform Changes After Reducing Heart Rate With Esmolol in Septic Shock Patients
- First Posted Date
- 2014-07-14
- Last Posted Date
- 2015-08-07
- Lead Sponsor
- University of Roma La Sapienza
- Target Recruit Count
- 45
- Registration Number
- NCT02188888
- Locations
- 🇮🇹
Department of Anesthesiology and Intensive care of the University of Rome La Sapienza, Rome, Italy
Concomitant Milrinone and Esmolol Treatment in Patients With Acute Myocardial Infarction
- Conditions
- Interventions
- First Posted Date
- 2014-03-28
- Last Posted Date
- 2017-10-09
- Lead Sponsor
- Ming-He Huang
- Registration Number
- NCT02098629
- Locations
- 🇨🇳
Yuebei People's Hospital, Shaoguan, Guangdong, China
Esmolol Effects on Heart and Inflammation in Septic Shock
- First Posted Date
- 2014-02-21
- Last Posted Date
- 2016-01-28
- Lead Sponsor
- Central Hospital, Nancy, France
- Target Recruit Count
- 25
- Registration Number
- NCT02068287
- Locations
- 🇫🇷
CHU de Nancy, Nancy, France
The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea
- Conditions
- Interventions
- First Posted Date
- 2014-02-13
- Last Posted Date
- 2014-11-10
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 47
- Registration Number
- NCT02062333
- Locations
- 🇹🇷
Kayseri Education and Research Hospital, Kayseri, Turkey
Nicardipine vs Esmolol Craniotomy Emergence
- First Posted Date
- 2013-09-27
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 40
- Registration Number
- NCT01951950
- Locations
- 🇺🇸
Northwestern Memorial Hospital, Chicago, Illinois, United States
Esmolol Pretreatment on Pain During Injection of Propofol
- Conditions
- Interventions
- First Posted Date
- 2013-06-25
- Last Posted Date
- 2016-02-08
- Lead Sponsor
- Kyungpook National University Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT01885364
- Locations
- 🇰🇷
Kyungpook National University Hospital, Daegu, Korea, Republic of
Effect of Esmolol on Pain Due to Rocuronium
- Conditions
- Interventions
- First Posted Date
- 2013-04-05
- Last Posted Date
- 2019-10-04
- Lead Sponsor
- Ankara Diskapi Training and Research Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT01824758
- Locations
- 🇹🇷
Diskapi Teaching and Research Hospital, Ankara, Altindag, Turkey
Drug Development Updates
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