Foscarnet
- Generic Name
- Foscarnet
- Brand Names
- Foscavir
- Drug Type
- Small Molecule
- Chemical Formula
- CH3O5P
- CAS Number
- 4428-95-9
- Unique Ingredient Identifier
- 364P9RVW4X
- Background
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
- Indication
For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.
- Associated Conditions
- Chickenpox, Cytomegalovirus Retinitis, Herpes Simplex Infections
- Associated Therapies
- -
CMV-CTL for the Treatment of CMV Infection After HSCT
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2016-12-28
- Last Posted Date
- 2023-04-25
- Target Recruit Count
- 5
- Registration Number
- NCT03004261
- Locations
- 🇨🇳
Shanghai Jiao Tong University Affilated Shanghai General Hospital, Shanghai, Shanghai, China
Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 2016-10-13
- Last Posted Date
- 2021-11-03
- Lead Sponsor
- Shire
- Target Recruit Count
- 352
- Registration Number
- NCT02931539
- Locations
- 🇺🇸
University of Maryland, Baltimore, Maryland, United States
🇺🇸Johns Hopkins Hospital, Baltimore, Maryland, United States
🇺🇸University of Southern California, Los Angeles, California, United States
Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 1999-09-24
- Last Posted Date
- 2015-09-14
- Lead Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Target Recruit Count
- 279
- Registration Number
- NCT00000134
Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT)
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 1999-09-24
- Last Posted Date
- 2015-10-22
- Lead Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Target Recruit Count
- 234
- Registration Number
- NCT00000136
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