Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone.
Morphine was granted FDA approval in 1941.
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Thoracic Epidural Analgesia in Flail Chest
- First Posted Date
- 2018-01-29
- Last Posted Date
- 2018-01-29
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 40
- Registration Number
- NCT03413059
TAP vs QLB in Patients After Cesarean Delivery
- First Posted Date
- 2018-01-19
- Last Posted Date
- 2023-11-24
- Lead Sponsor
- Medical University of Lublin
- Target Recruit Count
- 105
- Registration Number
- NCT03404908
- Locations
- 🇵🇱
II Department of Anesthesia and Intensive Care, Medical University of Lublin, Lublin, Poland
Effect of Morphine on Dyspnea and 6-Minute Walk Distance in Pulmonary Arterial Hypertension
- First Posted Date
- 2018-01-17
- Last Posted Date
- 2018-01-18
- Lead Sponsor
- John Granton
- Target Recruit Count
- 15
- Registration Number
- NCT03401476
- Locations
- 🇨🇦
University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain
- First Posted Date
- 2018-01-11
- Last Posted Date
- 2024-11-06
- Lead Sponsor
- Henrietta Bada
- Target Recruit Count
- 120
- Registration Number
- NCT03396588
- Locations
- 🇺🇸
Kentucky Children's Hospital, Lexington, Kentucky, United States
Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
- Conditions
- Interventions
- First Posted Date
- 2017-12-26
- Last Posted Date
- 2020-01-13
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 26
- Registration Number
- NCT03383588
- Locations
- 🇺🇸
Albert Einstein College of Medicine/ Montefiore Medical Center, Bronx, New York, United States
Post-operative Pain Relief in Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2017-11-28
- Last Posted Date
- 2017-11-28
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 120
- Registration Number
- NCT03355716
Ultrasound-Guided Versus Conventional Injection for Caudal Block
- Conditions
- Interventions
- First Posted Date
- 2017-11-08
- Last Posted Date
- 2017-11-09
- Lead Sponsor
- Ataturk University
- Target Recruit Count
- 134
- Registration Number
- NCT03337191
- Locations
- 🇹🇷
Ataturk University, Erzurum, Turkey
Methadone Associated With Morphine for Cancer Pain
- First Posted Date
- 2017-10-30
- Last Posted Date
- 2017-10-30
- Lead Sponsor
- Federal University of São Paulo
- Target Recruit Count
- 40
- Registration Number
- NCT03324815
- Locations
- 🇧🇷
Rioko K Sakata, São Paulo, Brazil
Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy
- First Posted Date
- 2017-09-20
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT03288428
- Locations
- 🇨🇳
First hospital Peking University, Beijing, Beijing, China
Intravenous Buprenorphine Versus Morphine for Severe Pain in the Emergency Department
- First Posted Date
- 2017-08-22
- Last Posted Date
- 2017-10-19
- Lead Sponsor
- Alameda Health System
- Target Recruit Count
- 122
- Registration Number
- NCT03256487
- Locations
- 🇺🇸
Alameda Health System, Highland Hospital, Oakland, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.