Fluticasone propionate

Generic Name
Fluticasone propionate
Brand Names
Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
Drug Type
Small Molecule
Chemical Formula
C25H31F3O5S
CAS Number
80474-14-2
Unique Ingredient Identifier
O2GMZ0LF5W
Background

Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.

Indication

Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.

Associated Conditions
Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
Associated Therapies
-

Study to Analyse Difference in Bioavailability Between MP29-02 and Fluticasone Propionate

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2016-08-30
Last Posted Date
2021-07-13
Lead Sponsor
University Hospital, Ghent
Registration Number
NCT02883439
Locations
🇧🇪

University Hospital Ghent, departement otorhinolaryngology, Ghent, Belgium

Ciclesonide vs Fluticasone Nasal Sprays in Nasal Poplyposis

First Posted Date
2016-01-28
Last Posted Date
2016-01-28
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
32
Registration Number
NCT02665806

Effect of Extra- Fine Versus Coarse-Particle Inhaled Corticosteroids (ICS) on Ventilation Heterogeneity in Children With Poorly Controlled Asthma

Phase 4
Completed
Conditions
Interventions
First Posted Date
2015-10-16
Last Posted Date
2018-10-25
Lead Sponsor
University of Virginia
Target Recruit Count
31
Registration Number
NCT02577497
Locations
🇺🇸

University of Virginia - Fontaine Research Park, Charlottesville, Virginia, United States

Nebulized Corticosteroid for Post Extubation Stridor in Children

Phase 3
Completed
Conditions
Interventions
First Posted Date
2015-08-14
Last Posted Date
2017-04-27
Lead Sponsor
Ramathibodi Hospital
Target Recruit Count
144
Registration Number
NCT02523820
Locations
🇹🇭

Department of Pediatric,Ramathibodi Hospital, Bangkok, Thailand

A Bronchoscopy Study to Assess the Effects of Inhaled Corticosteroids on Adult Healthy Volunteers

Phase 4
Active, not recruiting
Conditions
Interventions
First Posted Date
2015-06-19
Last Posted Date
2023-12-06
Lead Sponsor
University Hospitals, Leicester
Target Recruit Count
30
Registration Number
NCT02476825
Locations
🇬🇧

University Hospitals of Leicester NHS Trust, Leicester, Leics, United Kingdom

Bioequivalence Study of Synflutide HFA Inhaler and Seretide Evohaler in Healthy Volunteers Without Charcoal Block

First Posted Date
2015-06-09
Last Posted Date
2016-07-26
Lead Sponsor
Intech Biopharm Ltd.
Target Recruit Count
45
Registration Number
NCT02466347
Locations
🇨🇳

Clinical Pharmacology Unit of Mackay Memorial Hospital Tamshui Branch, New Taipei City, Taiwan

Bioequivalence Study of Synflutide HFA Inhaler and Seretide Evohaler in Healthy Volunteers With Charcoal Block

First Posted Date
2015-06-09
Last Posted Date
2015-06-09
Lead Sponsor
Intech Biopharm Ltd.
Target Recruit Count
45
Registration Number
NCT02466503
Locations
🇨🇳

Clinical Pharmacology Unit of Mackay Memorial Hospital Tamshui Branch, New Taipei City, Taiwan

A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma

First Posted Date
2015-05-18
Last Posted Date
2019-01-14
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
423
Registration Number
NCT02446418
Locations
🇩🇪

GSK Investigational Site, Magdeburg, Germany

Factors Involved in Dymista's Superior Clinical Efficacy in the Treatment of Seasonal Allergic Rhinitis

First Posted Date
2015-03-30
Last Posted Date
2024-10-17
Lead Sponsor
University of Chicago
Target Recruit Count
22
Registration Number
NCT02402465
Locations
🇺🇸

The University of Chicago Medicine, Chicago, Illinois, United States

Clinical Equivalence Study of Fluticasone Propionate Nasal Spray, 50 mcg/Actuation vs. Flonase in Allergic Rhinitis Patients

First Posted Date
2014-09-23
Last Posted Date
2023-06-08
Lead Sponsor
Teva Pharmaceuticals USA
Target Recruit Count
1474
Registration Number
NCT02246920
Locations
🇺🇸

Novum Pharmaceutical Research Services, Pittsburgh, Pennsylvania, United States

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