Haloperidol

Generic Name: Haloperidol

Brand Names: Haldol

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₃ClFNO_₂

CAS Number: 52-86-8

Unique Ingredient Identifier: J6292F8L3D

Background: Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularl...

Indication: Haloperidol is indicated for a number of conditions including for the treatment of schizophrenia, for the manifestations of psychotic disorders, for the control of tics and vocal utterances of Tourette’s Disorder in children and adults, for treatment of severe behavior problems in children of combative, explosive hyperexcitability (which cannot be accounted ...

Associated Conditions: Aggression, Delirium, Gilles de la Tourette's Syndrome, Huntington's Disease (HD), Nausea and vomiting, Obsessive Compulsive Disorder (OCD), Psychosis, Schizophrenia, Severe Disruptive Behaviour Disorders, Severe Hyperactivity

Associated Therapies: -

Clinical Trials

Schizophrenia Drug Could Be Biggest Breakthrough Since 1950s

New schizophrenia treatment, Cobenfy, approved by FDA targets brain's acetylcholine levels, reducing side effects like drowsiness and weight gain, and could begin prescriptions in late October.

abcnews.go.com

3 months ago

FDA approves 1st new drug for schizophrenia in more than 30 years

FDA approves Cobenfy, first new schizophrenia drug in over 30 years, combining xanomeline and trospium chloride to manage symptoms via a different mechanism targeting acetylcholine, potentially reducing common side effects like weight gain and drowsiness.

Drug Development Updates

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