Haloperidol
- Generic Name
- Haloperidol
- Brand Names
- Haldol
- Drug Type
- Small Molecule
- Chemical Formula
- C21H23ClFNO2
- CAS Number
- 52-86-8
- Unique Ingredient Identifier
- J6292F8L3D
- Background
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularl...
- Indication
Haloperidol is indicated for a number of conditions including for the treatment of schizophrenia, for the manifestations of psychotic disorders, for the control of tics and vocal utterances of Tourette’s Disorder in children and adults, for treatment of severe behavior problems in children of combative, explosive hyperexcitability (which cannot be accounted ...
- Associated Conditions
- Aggression, Delirium, Gilles de la Tourette's Syndrome, Huntington's Disease (HD), Nausea and vomiting, Obsessive Compulsive Disorder (OCD), Psychosis, Schizophrenia, Severe Disruptive Behaviour Disorders, Severe Hyperactivity
- Associated Therapies
- -
Evaluation of Negative Symptoms and Cognitive Function After Administration of Antipsychotics in Healthy Volunteer
- Conditions
- Interventions
- First Posted Date
- 2010-08-20
- Last Posted Date
- 2010-08-20
- Lead Sponsor
- Chonbuk National University Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT01185418
- Locations
- 🇰🇷
Chonbuk national university hospital, Jeonju, Korea, Republic of
Clinical Effectiveness of Newer Antipsychotics in Comparison With Conventional Antipsychotics in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2010-07-16
- Last Posted Date
- 2015-06-22
- Lead Sponsor
- University of Bremen
- Target Recruit Count
- 149
- Registration Number
- NCT01164059
- Locations
- 🇩🇪
Klinikum Bremen-Ost gGmbH, Bremen, Germany
🇩🇪Rheinische Kliniken Düsseldorf der Heinrich-Heine-Universität, Düsseldorf, Germany
🇩🇪Privat-Nerven-Klinik Dr. med. Kurt Fontheim, Liebenburg, Germany
Effects of Aripiprazole and Haloperidol on Mesolimbic System Functioning
- Conditions
- Interventions
- First Posted Date
- 2010-07-13
- Last Posted Date
- 2014-09-12
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 54
- Registration Number
- NCT01161277
- Locations
- 🇳🇴
Oslo University Hospital, Ullevål, Oslo, Norway
Customized Adherence Enhancement Plus Long-acting Injectable Antipsychotic
- Conditions
- Interventions
- First Posted Date
- 2010-06-29
- Last Posted Date
- 2014-12-30
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT01152697
- Locations
- 🇺🇸
University Hosptials, Cleveland, Ohio, United States
Dexmedetomidine for the Treatment of Delirium After Heart Surgery
- Conditions
- Interventions
- First Posted Date
- 2010-06-09
- Last Posted Date
- 2016-11-01
- Lead Sponsor
- Thorax-Kärlkliniken
- Target Recruit Count
- 3
- Registration Number
- NCT01140529
- Locations
- 🇸🇪
ThoraxKärlkliniken, Universitetssjukhuset, Linköping, Sweden
Clozapine and Olanzapine Treatment of Aggression
- Conditions
- Interventions
- First Posted Date
- 2010-05-14
- Last Posted Date
- 2010-05-14
- Lead Sponsor
- Nathan Kline Institute for Psychiatric Research
- Target Recruit Count
- 110
- Registration Number
- NCT01123408
- Locations
- 🇺🇸
Nathan Kline Institute, Orangeburg, New York, United States
Pragmatic RCT Comparing Aripiprazole, Olanzapine and Haloperidol in the Treatment of Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2010-01-20
- Last Posted Date
- 2014-04-10
- Target Recruit Count
- 300
- Registration Number
- NCT01052389
- Locations
- 🇮🇹
Department of Mental Health, Genoa, Liguria, Italy
A Double-blind, Randomized, Controlled Trial of Quetiapine Versus Haloperidol for the Treatment of Delirium
- First Posted Date
- 2009-08-07
- Last Posted Date
- 2011-06-23
- Lead Sponsor
- Chiang Mai University
- Target Recruit Count
- 52
- Registration Number
- NCT00954603
- Locations
- 🇹🇭
Department of psychiatry, faculty of medicine, Chiang Mai university, Chiang Mai, Thailand
Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol Intramuscular (IM) Injection for Treatment of Acute Psychotic Agitation in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2009-03-11
- Last Posted Date
- 2009-08-03
- Lead Sponsor
- Central South University
- Target Recruit Count
- 198
- Registration Number
- NCT00859872
- Locations
- 🇨🇳
MentalHealth Institute of the 2nd Xiangya Hospital, Central South University, Changsha, Hunan, China
Pharmacological Management of Delirium
- Conditions
- Interventions
- First Posted Date
- 2009-02-12
- Last Posted Date
- 2018-08-17
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 551
- Registration Number
- NCT00842608
- Locations
- 🇺🇸
Eskenazi Hospital, Indianapolis, Indiana, United States
🇺🇸Methodist Hospital, Indianapolis, Indiana, United States
🇺🇸University Hospital, Indianapolis, Indiana, United States
Drug Development Updates
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