Phenprocoumon
- Generic Name
- Phenprocoumon
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H16O3
- CAS Number
- 435-97-2
- Unique Ingredient Identifier
- Q08SIO485D
- Background
Coumarin derivative that acts as a long-acting oral anticoagulant.
- Indication
Used for the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
- Associated Conditions
- Myocardial Infarction, Thrombosis, Venous Embolism
- Associated Therapies
- -
Real-world Comparative Effectiveness of Stroke Prevention in Patients With Atrial Fibrillation Treated With Factor Xa Non-vitamin-K Oral Anticoagulants (NOACs) vs. Phenprocoumon
- Conditions
- Interventions
- First Posted Date
- 2018-06-20
- Last Posted Date
- 2020-11-27
- Lead Sponsor
- Bayer
- Target Recruit Count
- 64920
- Registration Number
- NCT03563937
- Locations
- 🇩🇪
Many Locations, Multiple Locations, Germany
Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy
- First Posted Date
- 2018-03-13
- Last Posted Date
- 2021-07-30
- Lead Sponsor
- Charite University, Berlin, Germany
- Target Recruit Count
- 1512
- Registration Number
- NCT03463317
- Locations
- 🇩🇪
Vivantes Klinik Am Urban, Kardiologie, Berlin, Germany
🇩🇪Charité Universitätsmedizin Berlin, CBF, Kardiologie, Berlin, Germany
🇩🇪Vivantes Klinikum Neukölln, Kardiologie, Berlin, Germany
Compare Apixaban and Vitamin-K Antagonists in Patients With Atrial Fibrillation (AF) and End-Stage Kidney Disease (ESKD)
- Conditions
- Interventions
- First Posted Date
- 2016-10-14
- Last Posted Date
- 2022-09-27
- Lead Sponsor
- Atrial Fibrillation Network
- Target Recruit Count
- 108
- Registration Number
- NCT02933697
- Locations
- 🇩🇪
Universitätsklinikum Münster, Münster, Germany
Dabigatran as an Alternative Anticoagulant in Patients With Left Ventricular Assist Device (LVAD)
- First Posted Date
- 2016-08-19
- Last Posted Date
- 2016-08-19
- Lead Sponsor
- Daniel Zimpfer, MD
- Target Recruit Count
- 16
- Registration Number
- NCT02872649
- Locations
- 🇦🇹
Medical Univerity Vienna, Vienna, Austria
Left Atrial Thrombus Reduction - Effect of Dabigatran Versus Phenprocoumon
- Conditions
- Interventions
- First Posted Date
- 2015-10-29
- Last Posted Date
- 2015-11-13
- Lead Sponsor
- University of Ulm
- Target Recruit Count
- 40
- Registration Number
- NCT02591225
- Locations
- 🇩🇪
Department of Internal Medicine II, University Hospital Ulm, Ulm, Germany
Resolution of Left Atrial-Appendage Thrombus - Effects of Dabigatran in Patients With AF
- Conditions
- Interventions
- First Posted Date
- 2014-10-06
- Last Posted Date
- 2019-07-26
- Lead Sponsor
- Johannes Gutenberg University Mainz
- Target Recruit Count
- 64
- Registration Number
- NCT02256683
- Locations
- 🇩🇪
Universitätsmedizin Leipzig, Leipzig, Germany
🇩🇪Charité Universitätsmedizin Berlin, Berlin, Germany
🇩🇪University Heart Center; Department of Cardiology and Angiology II, Bad Krozingen, Germany
A Study of the Effect of Vemurafenib on the Pharmacokinetics of Phenprocoumon in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy
- Conditions
- Interventions
- First Posted Date
- 2013-05-08
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 2
- Registration Number
- NCT01849666
Impact of Dabigatran and Phenprocoumon on Clopidogrel Mediated ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2011-05-12
- Last Posted Date
- 2015-02-05
- Lead Sponsor
- Deutsches Herzzentrum Muenchen
- Target Recruit Count
- 46
- Registration Number
- NCT01352702
- Locations
- 🇩🇪
Deutsches Herzzentrum Muenchen, Munich, Germany
Impact of Dabigatran and Phenprocoumon on ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation
- First Posted Date
- 2011-04-21
- Last Posted Date
- 2013-07-02
- Lead Sponsor
- Deutsches Herzzentrum Muenchen
- Target Recruit Count
- 70
- Registration Number
- NCT01339819
- Locations
- 🇩🇪
Deutsches Herzzentrum Muenchen, Munich, Germany
D-Dimer Guided Oral Anticoagulant Treatment (OAT)
- First Posted Date
- 2009-05-08
- Last Posted Date
- 2009-05-08
- Lead Sponsor
- University Hospital, Bonn
- Target Recruit Count
- 300
- Registration Number
- NCT00895505
- Locations
- 🇩🇪
Institut für Experimentelle Hämatologie und Transfusionsmedizin, Universitätsklinikum Bonn, Bonn, Nordrhein-Westfalen, Germany
Drug Development Updates
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