Voclosporin
- Generic Name
- Voclosporin
- Brand Names
- Lupkynis
- Drug Type
- Small Molecule
- Chemical Formula
- C63H111N11O12
- CAS Number
- 515814-01-4
- Unique Ingredient Identifier
- 2PN063X6B1
- Background
Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed with SLE, 5-20% of those suffering from LN develop end-stage kidney disease, a fatal condition. Early and accurate interve...
- Indication
联合免疫抑制疗法治疗成人活动性狼疮肾炎（LN）。
- Associated Conditions
- Lupus Nephritis
- Associated Therapies
- -
Special Access for the Use of Voclosporin for Kidney Transplantation
- Conditions
- First Posted Date
- 2010-11-07
- Last Posted Date
- 2024-02-22
- Lead Sponsor
- Weill Medical College of Cornell University
- Registration Number
- NCT01236287
- Locations
- 🇺🇸
Weill Cornell Medical College/NewYork-Presbyterian Hospital, New York, New York, United States
Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients
- First Posted Date
- 2006-12-06
- Last Posted Date
- 2009-07-30
- Lead Sponsor
- Aurinia Pharmaceuticals Inc.
- Target Recruit Count
- 642
- Registration Number
- NCT00408187
- Locations
- 🇵🇱
Isotechnika Investigational Site, Zabrze, Poland
Study of ISA247 (Voclosporin) in De Novo Renal Transplantation
- First Posted Date
- 2005-12-28
- Last Posted Date
- 2013-02-12
- Lead Sponsor
- Aurinia Pharmaceuticals Inc.
- Target Recruit Count
- 334
- Registration Number
- NCT00270634
- Locations
- 🇨🇦
Isotechnika Investigational Site, Saskatoon, Saskatchewan, Canada
A 36-Week Extension to Protocol ISA04-03
- First Posted Date
- 2005-11-28
- Last Posted Date
- 2008-09-29
- Lead Sponsor
- Aurinia Pharmaceuticals Inc.
- Target Recruit Count
- 309
- Registration Number
- NCT00258713
- Locations
- 🇨🇦
Isotechnika Investigational Site, Sherbrooke, Quebec, Canada
Randomized Placebo-controlled Study of ISA247 in Plaque Psoriasis
- First Posted Date
- 2005-10-27
- Last Posted Date
- 2023-03-27
- Lead Sponsor
- Aurinia Pharmaceuticals Inc.
- Target Recruit Count
- 451
- Registration Number
- NCT00244842
- Locations
- 🇨🇦
Isotechnika Investigational Site, Ste. Foy, Quebec, Canada
🇨🇦Isotechnika Investigational Site', Edmonton, Alberta, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.