Ibuprofen

Generic Name
Ibuprofen
Brand Names
Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
Drug Type
Small Molecule
Chemical Formula
C13H18O2
CAS Number
15687-27-1
Unique Ingredient Identifier
WK2XYI10QM
Background

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...

Indication

Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...

Associated Conditions
Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
Associated Therapies
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Non-Steroidal Anti-Inflammatory Drugs in Acute Myocarditis

Phase 3
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-11-13
Last Posted Date
2024-11-13
Lead Sponsor
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Target Recruit Count
150
Registration Number
NCT06686862
Locations
🇪🇸

Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain

Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial

First Posted Date
2024-11-04
Last Posted Date
2024-11-04
Lead Sponsor
University of Michigan
Target Recruit Count
900
Registration Number
NCT06671002
Locations
🇺🇸

Children's Hospital Los Angeles (CHLA), Los Angeles, California, United States

🇺🇸

Lucile Packard Children's Hospital Stanford, Palo Alto, California, United States

🇺🇸

University of Michigan, Ann Arbor, Michigan, United States

and more 1 locations

Comparison of IV Nalbuphine Versus Ibuprofen for Postoperative Pain Control in Cesarean Section

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2024-09-13
Last Posted Date
2024-09-13
Lead Sponsor
Muhammad Aamir Latif
Target Recruit Count
80
Registration Number
NCT06594224
Locations
🇵🇰

Nishtar Hospital, Multan, Punjab, Pakistan

🇵🇰

Nishtar Medical University, Multan, Punjab, Pakistan

Efficacy and Safety in the Combination of Ibuprofen / Loratadine Versus Ibuprofen Versus Loratadine

First Posted Date
2024-08-01
Last Posted Date
2024-08-02
Lead Sponsor
Laboratorios Silanes S.A. de C.V.
Target Recruit Count
177
Registration Number
NCT06531707
Locations
🇲🇽

Laboratorio Silanes, S.A. de C.V., Mexico City, Mexico

Comparing the Difference in Pain Control in the Pediatric General Surgery Population: to Alternate or Combine Acetaminophen and Ibuprofen?

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-07-17
Last Posted Date
2024-07-22
Lead Sponsor
Baylor Research Institute
Target Recruit Count
80
Registration Number
NCT06505148
Locations
🇺🇸

Baylor Scott & White Health Temple Market, Temple, Texas, United States

Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction

First Posted Date
2024-07-03
Last Posted Date
2024-07-10
Lead Sponsor
United States Naval Medical Center, San Diego
Target Recruit Count
80
Registration Number
NCT06484439
Locations
🇺🇸

Naval Medical Center San Diego, San Diego, California, United States

Opioid Use After Laparoscopic Salpingectomy

First Posted Date
2024-05-30
Last Posted Date
2024-05-30
Lead Sponsor
Johns Hopkins University
Target Recruit Count
120
Registration Number
NCT06434233
Locations
🇺🇸

Johns Hopkins Bayview Medical Center, Baltimore, Maryland, United States

Gynecologic Endoscopic Surgery of Female Motion Sickness Patients

First Posted Date
2024-01-31
Last Posted Date
2024-01-31
Lead Sponsor
Second Hospital of Jilin University
Target Recruit Count
66
Registration Number
NCT06232785
Locations
🇨🇳

Second Hospital of Jilin University, Changchun, Jilin, China

Efficacy of a Standardized Centella Asiatica Extract in Patients With Temporomandibular Disorder

First Posted Date
2024-01-30
Last Posted Date
2024-02-07
Lead Sponsor
Chulalongkorn University
Target Recruit Count
23
Registration Number
NCT06231212
Locations
🇹🇭

Chulalongkorn University, Bangkok, Thailand

SCHF Post-Op Study Between Opioid and Non-Opioid Pain Management

First Posted Date
2024-01-02
Last Posted Date
2024-01-10
Lead Sponsor
Children's Mercy Hospital Kansas City
Target Recruit Count
160
Registration Number
NCT06187584
Locations
🇺🇸

Children's Mercy Hospital & Clinics, Kansas City, Missouri, United States

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