Ibuprofen
- Generic Name
- Ibuprofen
- Brand Names
- Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18O2
- CAS Number
- 15687-27-1
- Unique Ingredient Identifier
- WK2XYI10QM
- Background
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...
- Indication
Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...
- Associated Conditions
- Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
- Associated Therapies
- -
The Effect of Combined Oral and Topical Analgesics to Reduce Pain Perception During Electrodiagnostic Testing
- Conditions
- Interventions
- First Posted Date
- 2020-04-08
- Last Posted Date
- 2023-02-28
- Lead Sponsor
- Aga Khan University Hospital, Pakistan
- Target Recruit Count
- 113
- Registration Number
- NCT04337814
- Locations
- 🇵🇰
Aga khan University Hospital, Karachi, Sindh, Pakistan
LIBERATE Trial in COVID-19
- Conditions
- Interventions
- First Posted Date
- 2020-04-06
- Last Posted Date
- 2023-07-25
- Lead Sponsor
- King's College London
- Registration Number
- NCT04334629
- Locations
- 🇬🇧
Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
Probiotic Intervention After Surgical Removal of Mandibular Third Molars
- Conditions
- Interventions
- First Posted Date
- 2019-12-18
- Last Posted Date
- 2020-05-06
- Lead Sponsor
- AB Biotics, SA
- Target Recruit Count
- 38
- Registration Number
- NCT04203771
- Locations
- 🇪🇸
Hospital de Nens de Barcelona (Children's Hospital of Barcelona)), Barcelona, Spain
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis
- Conditions
- Interventions
- First Posted Date
- 2019-11-08
- Last Posted Date
- 2022-08-29
- Lead Sponsor
- Walter Reed National Military Medical Center
- Target Recruit Count
- 3
- Registration Number
- NCT04157036
- Locations
- 🇺🇸
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
Ibuprofen Versus Ketorolac by Mouth in the Treatment of Acute Pain From Osteoarticular Trauma
- First Posted Date
- 2019-10-21
- Last Posted Date
- 2022-01-06
- Lead Sponsor
- IRCCS Burlo Garofolo
- Target Recruit Count
- 212
- Registration Number
- NCT04133623
- Locations
- 🇮🇹
Azienda Ospedaliera Santa Maria degli Angeli, Pordenone, Italy
🇮🇹Institute for Maternal and Child Health - IRCCS Burlo Garofolo-, Trieste, Italy
🇮🇹Ospedale Santa Maria della Misericordia, Udine, Italy
Acute Low Back Pain in the Emergency Department Treated With Osteopathic Manipulative Treatment Versus NSAIDs
- Conditions
- Interventions
- First Posted Date
- 2019-10-16
- Last Posted Date
- 2022-11-07
- Lead Sponsor
- Albert Einstein Healthcare Network
- Target Recruit Count
- 174
- Registration Number
- NCT04129437
- Locations
- 🇺🇸
AEHN, Philadelphia, Pennsylvania, United States
Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2019-10-11
- Last Posted Date
- 2023-06-01
- Lead Sponsor
- Naestved Hospital
- Target Recruit Count
- 1060
- Registration Number
- NCT04123873
- Locations
- 🇩🇰
Køge Hospital, Køge, Denmark
🇩🇰Næstved-Slagelse-Ringsted Hospitals, Næstved, Danmark, Denmark
🇩🇰Gentofte Hospital, Hellerup, Denmark
Paracetamol Versus Ibuprofen in Premature Infants With Hemodynamically Significant Patent Ductus Arteriosus
- Conditions
- Interventions
- First Posted Date
- 2019-07-30
- Last Posted Date
- 2019-07-30
- Lead Sponsor
- Máximo Vento Torres
- Target Recruit Count
- 300
- Registration Number
- NCT04037514
- Locations
- 🇪🇸
Hospital Reina Sofía, Córdoba, Cordoba, Spain
🇪🇸Hospital Universitario de Cabueñes, Gijón, Spain
🇪🇸Hospital Universitari i Politècnic La Fe, Valencia, Spain
ICE T for Post GYN Surgery Pain
- Conditions
- Interventions
- First Posted Date
- 2019-06-14
- Last Posted Date
- 2022-05-02
- Lead Sponsor
- MetroHealth Medical Center
- Target Recruit Count
- 66
- Registration Number
- NCT03987022
- Locations
- 🇺🇸
MetroHealth Medical Center, Cleveland, Ohio, United States
Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen
- Conditions
- Interventions
- First Posted Date
- 2019-06-05
- Last Posted Date
- 2023-08-31
- Lead Sponsor
- Heron Therapeutics
- Target Recruit Count
- 116
- Registration Number
- NCT03974932
- Locations
- 🇺🇸
Endeavor Clinical Trials, LLC., San Antonio, Texas, United States
🇺🇸Helen Keller Hospital, Sheffield, Alabama, United States
🇺🇸Phoenix Clinical Research, LLC, Tamarac, Florida, United States
Drug Development Updates
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