Cetrorelix

Generic Name: Cetrorelix

Brand Names: Cetrotide

Drug Type: Small Molecule

Chemical Formula: C_₇₀H_₉₂ClN_₁₇O_₁₄

CAS Number: 120287-85-6

Unique Ingredient Identifier: OON1HFZ4BA

Background: Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released. Cetrorelix does not allow the premature release of these eggs to occur.

Indication: For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation

Associated Conditions: -

Associated Therapies: Controlled Ovarian Stimulation

Clinical Trials

NATural Ovarian Stimulation

Phase 4

Completed

Conditions: Infertility

Interventions: Drug: Gonal-F®
Drug: Cetrotide®

First Posted Date: 2016-09-08

Last Posted Date: 2021-04-30

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 129

Registration Number: NCT02892942

Locations: 🇫🇷
Hôpital Antoine Béclère, Clamart, France

Outcome of Cetrotide Therapy for Management of Women at High-risk of Ovarian Hyperstimulation Syndrome

Phase 2

Conditions: Infertility

Interventions: Drug: Cetrorelix

First Posted Date: 2016-07-06

Last Posted Date: 2017-03-30

Lead Sponsor: Benha University

Target Recruit Count: 48

Registration Number: NCT02823080

Locations: 🇪🇬
Benha university hospitalا, Benha, El qalubia, Egypt

Gonadotropin Releasing Hormone Antagonist in Treatment of Early-onset Severe Ovarian Hyperstimulation Syndrome

Phase 2

Completed

Conditions: Assisted Reproduction

Interventions: Drug: Cetrorelix

First Posted Date: 2016-05-27

Last Posted Date: 2016-05-27

Lead Sponsor: Ain Shams University

Target Recruit Count: 84

Registration Number: NCT02784457

Dysregulation of FSH in Obesity: Functional and Statistical Analysis

Not Applicable

Completed

Conditions: Obesity
Fertility

Interventions: Drug: Degarelix (GnRH antagonist)
Drug: recombinant FSH
Drug: Cetrorelix

First Posted Date: 2015-06-23

Last Posted Date: 2024-06-05

Lead Sponsor: University of Colorado, Denver

Target Recruit Count: 99

Registration Number: NCT02478775

Locations: 🇺🇸
University of Colorado Clinical and Translational Research Center, Aurora, Colorado, United States

Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women

Early Phase 1

Completed

Conditions: Aging
Menopause

Interventions: Drug: KUVAN
Drug: Placebo
Drug: Cetrotide
Drug: Placebo transdermal patch
Drug: Climara

First Posted Date: 2014-01-22

Last Posted Date: 2019-07-11

Lead Sponsor: University of Colorado, Denver

Target Recruit Count: 100

Registration Number: NCT02042196

Locations: 🇺🇸
University of Colorado Denver, Aurora, Colorado, United States

Study on Influence of Leutinizing Hormone (LH) on Oocyte Maturity

Not Applicable

Conditions: Infertility

Interventions: Drug: Luprolide Acetate
Drug: Cetrorelix

First Posted Date: 2012-05-10

Last Posted Date: 2012-05-25

Lead Sponsor: Southern Cross Fertility Centre

Target Recruit Count: 300

Registration Number: NCT01595334

Locations: 🇮🇳
Disha Fertility & Surgical Hospital, Indore, Madhya Pradesh, India
🇮🇳
Southern Cross Fertility Center, Mumbai, Maharashtra, India
🇮🇳
Sat Kaival Hospital Pvt. Ltd., Anand, Gujarat, India