MedPath

SEL-302

Generic Name
SEL-302
Drug Type
Biotech
Background

SEL-302 is a recombinant adeno-associated virus vector-based gene therapy expressing the methylmalonyl-CoA mutase (MMUT) transgene.

A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA

Phase 1
Suspended
Conditions
Methylmalonic Acidemia (MMA)
Interventions
First Posted Date
2023-03-21
Last Posted Date
2023-05-08
Lead Sponsor
Selecta Biosciences, Inc.
Target Recruit Count
6
Registration Number
NCT05778877
Locations
🇺🇸

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma

Phase 1
Terminated
Conditions
Mesothelioma
Interventions
First Posted Date
2018-02-19
Last Posted Date
2019-11-22
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
5
Registration Number
NCT03436732
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levels

Phase 1
Completed
Conditions
Gout
Interventions
Biological: SEL-037
Biological: SEL-212
First Posted Date
2016-01-07
Last Posted Date
2017-01-30
Lead Sponsor
Selecta Biosciences, Inc.
Target Recruit Count
63
Registration Number
NCT02648269
Locations
🇺🇸

Orlando Clinical Research Center, Inc., Orlando, Florida, United States

🇺🇸

Miami Research Associates, Miami, Florida, United States

🇺🇸

SNBL Clinical Pharmacology Center Inc., Baltimore, Maryland, United States

and more 3 locations
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