那可丁

概览

Noscapine is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.

作用机制

Noscapine's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.

适应症

Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.

• Common Cold
• Cough
• Respiratory Diseases