MedPath

Cupric sulfate

Generic Name
Cupric sulfate
Brand Names
Concept Ob, Multitrace-4, Multitrace-5, Multrys, Tandem Plus
Drug Type
Small Molecule
Chemical Formula
CuO4S
CAS Number
7758-98-7
Unique Ingredient Identifier
KUW2Q3U1VV

Overview

Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4∙5H2O) and is also known as blue vitriol. The anhydrous salt is created by heating the hydrate to 150 °C (300 °F). Cupric sulfate is used primarily for agricultural purposes, as a pesticide, germicide, feed additive, and soil additive. Some of its secondary uses are as a raw material in the preparation of other copper compounds, as a reagent in analytic chemistry, as an electrolyte for batteries and electroplating baths, and in medical practice as a locally applied fungicide, bactericide, and astringent . Copper is an essential trace element and an important catalyst for heme synthesis and iron absorption. After zinc and iron, copper is the third most abundant trace element found in the human body. Copper is a noble metal and its properties include high thermal and electrical conductivity, low corrosion, alloying ability, and malleability. Copper is a component of intrauterine contraceptive devices (IUD) and the release of copper is necessary for their important contraceptive effects. The average daily intake of copper in the USA is approximately 1 mg Cu with the diet being a primary source . Interestingly, the dysregulation of copper has been studied with a focus on neurodegenerative diseases, such as Wilson’s disease, Alzheimer’s disease, and Parkinson’s disease. Data from clinical observations of the neurotoxic effects of copper may provide the basis for future treatments affecting copper and its homeostasis .

Indication

Elemental use in copper deficiency Copper and copper containing compounds are broadly used in medical practice. Metallic copper is used already for many years in dental fillings and in copper intrauterine devices (IUD) for reversible contraception. Ointments containing copper, which release copper ions that are absorbed by the skin in the management of cramps, disturbances of renal function, peripheral, venous hypostatic circulatory disturbances, rheumatic disease and swelling associated with trauma. There are also cosmetic facial creams containing copper as their main active ingredient .

Associated Conditions

  • Copper Deficiency

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
CarWin Pharmaceutical Associates, LLC
15370-105
ORAL
1 mg in 1 1
1/10/2024
Centurion Labs, LLC
23359-105
ORAL
1 mg in 1 1
1/22/2024
PureTek Corporation
59088-112
ORAL
0.8 mg in 1 1
1/11/2023
American Regent, Inc.
0517-8510
INTRAVENOUS
1.57 mg in 1 mL
4/25/2019
U.S. Pharmaceutical Corporation
52747-620
ORAL
800 ug in 1 1
7/13/2022
CarWin Pharmaceutical Associates, LLC
15370-104
ORAL
1 mg in 1 1
1/10/2024
U.S. Pharmaceutical Corporation
52747-621
ORAL
2 mg in 1 1
7/13/2022
CarWin Pharmaceutical Associates, LLC
15370-101
ORAL
1 mg in 1 mL
8/3/2017
Exeltis USA, Inc.
0642-0207
ORAL
1.5 mg in 1 1
1/2/2023
PureTek Corporation
59088-643
ORAL, CUTANEOUS
0.8 mg in 1 1
2/14/2023

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
SALZMANN PRODUCT B-2 BIASOLT
biocentre
00696420
Powder - Oral
6 X / X
12/31/1986
MULTI VITAMIN MINERAL TAB
nutristar health products (1987) inc.
00474800
Tablet - Oral
2 MG / TAB
12/31/1979
SPASCUPREEL INJEEL LIQ
02026384
Liquid - Oral
6 D / AMP
12/31/1993
SPASCUPREEL TABLETS
02029723
Tablet - Oral
6 D
12/31/1993
LPCC COMP - DROPS
weleda ag heilmittelbetriebe
02174162
Liquid ,  Drops - Oral
3 D / ML
4/9/1998
SPASCUPREEL - TAB
02227746
Tablet - Oral
6 D
10/11/1996
EAU RESOLUTIVE SOKER
produits francais labs inc.
00166278
Liquid - Topical
28.925 MG / 30 G
12/31/1930
COMPLETE FORMULA FOR ADULTS TAB
ksl pharmaceuticals
02047527
Tablet - Oral
2 MG / TAB
12/31/1995
ALLIUM/CUPRUM SULFURICUM COMP - DROPS
weleda ag heilmittelbetriebe
02173891
Drops ,  Liquid - Oral
3 D / ML
4/6/1998
ONE A DAY ADVANCE ADULTS 50 PLUS TAB
miles canada inc. - consumer health care division
02080702
Tablet - Oral
2 MG / TAB
12/31/1994

CIMA AEMPS Drug Approvals

Approved Product
Company
Registration Number
Pharmaceutical Form
Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product
Company
Registration Number
Dosage Form
Strength
Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name
MA Holder
MA Number
Pharmaceutical Form
Active Ingredient
Authorization Date
No UK EMC drug information found for this drug.

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