Clevidipine
- Generic Name
- Clevidipine
- Brand Names
- Cleviprex
- Drug Type
- Small Molecule
- Chemical Formula
- C21H23Cl2NO6
- CAS Number
- 167221-71-8
- Unique Ingredient Identifier
- 19O2GP3B7Q
- Background
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
- Indication
For the reduction of blood pressure when when oral antihypertensive therapy is not feasible or not desirable.
- Associated Conditions
- Hypertension
- Associated Therapies
- -
The Energy Dose Study
- Conditions
- Interventions
- First Posted Date
- 2011-06-08
- Last Posted Date
- 2022-06-10
- Lead Sponsor
- Emory University
- Target Recruit Count
- 12
- Registration Number
- NCT01369147
- Locations
- 🇺🇸
Emory University Hospital, Atlanta, Georgia, United States
Clevidipine for Vasoreactivity Evaluation of the Pulmonary Arterial Bed
- Conditions
- First Posted Date
- 2010-05-12
- Last Posted Date
- 2013-06-10
- Lead Sponsor
- North Texas Veterans Healthcare System
- Target Recruit Count
- 12
- Registration Number
- NCT01121458
- Locations
- 🇺🇸
VA North Texas Health Care System, Dallas, Texas, United States
The Efficacy and Safety of Cleviprex in Ventriculostomy Patients Requiring IV Antihypertensive Therapy
- Conditions
- First Posted Date
- 2010-01-05
- Last Posted Date
- 2019-08-14
- Lead Sponsor
- Methodist Healthcare
- Registration Number
- NCT01042574
- Locations
- 🇺🇸
Methodist Healthcare, University Hospital, Memphis, Tennessee, United States
A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients
- First Posted Date
- 2009-08-04
- Last Posted Date
- 2015-02-09
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 22
- Registration Number
- NCT00952081
- Locations
- 🇺🇸
NYU Langone Medical Center, Department of Anesthesiology, New York, New York, United States
Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)
- Conditions
- Interventions
- First Posted Date
- 2008-12-05
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 117
- Registration Number
- NCT00803634
- Locations
- 🇺🇸
The Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸Jackson Hospital, Montgomery, Alabama, United States
🇺🇸Louisiana State University Health Sciences Center, Baton Rouge, Louisiana, United States
Clevidipine Bolus Administration in the Treatment of Hypertensive Patients Undergoing Cardiac Surgery (SPRINT)
- First Posted Date
- 2008-12-01
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 30
- Registration Number
- NCT00799604
- Locations
- 🇺🇸
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States
🇺🇸Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)
- First Posted Date
- 2008-04-24
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 37
- Registration Number
- NCT00666328
- Locations
- 🇺🇸
Maine Medical Center, Portland, Massachusetts, United States
🇺🇸Henry Ford Hospital, Detroit, Michigan, United States
🇩🇪Universitatsklinikum Heidelberg, Heidelberg, Germany
Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY)
- First Posted Date
- 2006-08-29
- Last Posted Date
- 2014-05-22
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 131
- Registration Number
- NCT00369837
- Locations
- 🇺🇸
Pennsylvania Hospital, Philadelphia, Pennsylvania, United States
🇺🇸Good Samaritan Hospital, Baltimore, Maryland, United States
🇺🇸Providence Heart & Vascular Institute, d/b/a Providence St. Vincent Medical Center, Portland, Oregon, United States
Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP)
- First Posted Date
- 2004-10-08
- Last Posted Date
- 2014-05-06
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 739
- Registration Number
- NCT00093912
- Locations
- 🇺🇸
International Heart Institute/St. Patrick Hospital, Missoula, Montana, United States
🇺🇸Mt. Sinai Medical Center, New York, New York, United States
🇺🇸Jackson-Madison County General Hospital, Jackson, Tennessee, United States
Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC)
- First Posted Date
- 2004-10-08
- Last Posted Date
- 2014-05-06
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 739
- Registration Number
- NCT00093925
- Locations
- 🇺🇸
Mobile Infirmary Medical Center, Mobile, Alabama, United States
🇺🇸Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸Ochsner Clinic Foundation, New Orleans, Louisiana, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.