Fluconazole
- Generic Name
- Fluconazole
- Brand Names
- Diflucan
- Drug Type
- Small Molecule
- Chemical Formula
- C13H12F2N6O
- CAS Number
- 86386-73-4
- Unique Ingredient Identifier
- 8VZV102JFY
- Background
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal dr...
- Indication
Fluconazole can be administered in the treatment of the following fungal infections:
1) Vaginal yeast infections caused by Candida
2) Systemic Candida infections
3) Both esophageal and oropharyngeal candidiasis
4) Cryptococcal meningitis
5) UTI (urinary tract infection) by Candida
6) Peritonitis (inflammation of the peritoneum) caused by Candida
...
- Associated Conditions
- Candida intertrigo, Candida pneumonia, Candida urinary tract infection, Candidemia, Candidiasis, Coccidioidomycosis, Esophageal Candidiasis, Fungal Infections, Fungal peritonitis caused by Candida, Meningitis, Cryptococcal, Oropharyngeal Candidiasis, Peritoneal candidiasis, Pneumonia cryptococcal, Pruritus, Skin Irritation, Systemic Candida Infections caused by Candida, Vaginal Candidiasis, Disseminated Candidiasis
- Associated Therapies
- -
Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients
- First Posted Date
- 2006-03-20
- Last Posted Date
- 2024-06-14
- Lead Sponsor
- Kyoto University
- Registration Number
- NCT00304772
- Locations
- 🇯🇵
Department of Clinical Laboratory Medicine, Kyoto University Hospital, Kyoto, Japan
Prediction of Drug Interactions With CYP2C9 Substrates
- Conditions
- First Posted Date
- 2005-09-27
- Last Posted Date
- 2008-10-29
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 16
- Registration Number
- NCT00226538
- Locations
- 🇮🇱
Hadassah Medical Organization, Jerusalem, Israel
Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia
- Conditions
- Interventions
- First Posted Date
- 2005-09-19
- Last Posted Date
- 2008-01-02
- Lead Sponsor
- Astellas Pharma Inc
- Target Recruit Count
- 24
- Registration Number
- NCT00189709
Reducing Vaginal Infections in Women
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2010-03-18
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 400
- Registration Number
- NCT00170430
- Locations
- 🇰🇪
Ganjoni Municipal Communicable Diseases Control Centre, Mombasa, Kenya
Endothelial Hyperpolarization in Humans
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2018-08-15
- Lead Sponsor
- Emory University
- Target Recruit Count
- 174
- Registration Number
- NCT00166166
- Locations
- 🇺🇸
Emory University School of Medicine, Atlanta, Georgia, United States
Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis
- First Posted Date
- 2005-09-05
- Last Posted Date
- 2012-05-16
- Target Recruit Count
- 143
- Registration Number
- NCT00145249
- Locations
- 🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸Harbor-UCLA Medical Center, Los Angeles, California, United States
🇺🇸The University of Texas Health Science Center at Houston, Houston, Texas, United States
Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation
- Conditions
- First Posted Date
- 2004-03-31
- Last Posted Date
- 2010-04-02
- Lead Sponsor
- Fred Hutchinson Cancer Center
- Target Recruit Count
- 578
- Registration Number
- NCT00003883
- Locations
- 🇺🇸
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
🇺🇸University of Washington Medical Center, Seattle, Washington, United States
Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101)
- First Posted Date
- 2004-01-13
- Last Posted Date
- 2023-01-04
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 600
- Registration Number
- NCT00075803
- Locations
- 🇺🇸
Hackensack University Medical Center, Hackensack, New Jersey, United States
🇺🇸Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, United States
Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer
- Conditions
- First Posted Date
- 2003-09-18
- Last Posted Date
- 2016-12-15
- Lead Sponsor
- University of Miami
- Registration Number
- NCT00002533
- Locations
- 🇺🇸
Sylvester Cancer Center, University of Miami, Miami, Florida, United States
The Safety and Efficacy of Anidulafungin Versus Comparator in Patients With Candidemia and Invasive Candidiasis
- Conditions
- First Posted Date
- 2003-03-12
- Last Posted Date
- 2008-10-21
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 256
- Registration Number
- NCT00056368
- Locations
- 🇺🇸
Versicor, Inc., King of Prussia, Pennsylvania, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.