Fluconazole
- Generic Name
- Fluconazole
- Brand Names
- Diflucan
- Drug Type
- Small Molecule
- Chemical Formula
- C13H12F2N6O
- CAS Number
- 86386-73-4
- Unique Ingredient Identifier
- 8VZV102JFY
- Background
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal dr...
- Indication
Fluconazole can be administered in the treatment of the following fungal infections:
1) Vaginal yeast infections caused by Candida
2) Systemic Candida infections
3) Both esophageal and oropharyngeal candidiasis
4) Cryptococcal meningitis
5) UTI (urinary tract infection) by Candida
6) Peritonitis (inflammation of the peritoneum) caused by Candida
...
- Associated Conditions
- Candida intertrigo, Candida pneumonia, Candida urinary tract infection, Candidemia, Candidiasis, Coccidioidomycosis, Esophageal Candidiasis, Fungal Infections, Fungal peritonitis caused by Candida, Meningitis, Cryptococcal, Oropharyngeal Candidiasis, Peritoneal candidiasis, Pneumonia cryptococcal, Pruritus, Skin Irritation, Systemic Candida Infections caused by Candida, Vaginal Candidiasis, Disseminated Candidiasis
- Associated Therapies
- -
To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
- Conditions
- Interventions
- First Posted Date
- 2014-03-21
- Last Posted Date
- 2015-06-30
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 26
- Registration Number
- NCT02093728
- Locations
- 🇺🇸
Research Site, Overland Park, Kansas, United States
Micafungin Versus Fluconazole for Prevention of Invasive Fungal Disease in Living Donor Liver Transplant Recipients
- First Posted Date
- 2013-11-01
- Last Posted Date
- 2013-11-01
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 172
- Registration Number
- NCT01974375
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
High Dose Fluconazole in Cutaneous Leishmaniasis in Bahia and Manaus
- Conditions
- Interventions
- First Posted Date
- 2013-10-01
- Last Posted Date
- 2015-12-02
- Lead Sponsor
- Hospital Universitário Professor Edgard Santos
- Target Recruit Count
- 53
- Registration Number
- NCT01953744
- Locations
- 🇧🇷
Posto de Saúde de Corte de Pedra, Presidente Tancredo Neves, Bahia, Brazil
Evaluation of Budesonide and How It Interacts With Antifungal Drugs in People With Gastrointestinal Graft-Versus-Host Disease
- Conditions
- Interventions
- First Posted Date
- 2013-09-25
- Last Posted Date
- 2021-03-12
- Target Recruit Count
- 15
- Registration Number
- NCT01950507
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
A Study of Baricitinib When Administered With Ketoconazole or Fluconazole in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2013-08-16
- Last Posted Date
- 2017-06-06
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 36
- Registration Number
- NCT01924299
- Locations
- 🇬🇧
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Leeds, West Yorkshire, United Kingdom
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Acute Vaginal Candidiasis (Yeast Infection)
- First Posted Date
- 2013-07-03
- Last Posted Date
- 2018-08-01
- Lead Sponsor
- Viamet
- Target Recruit Count
- 55
- Registration Number
- NCT01891331
- Locations
- 🇺🇸
Healthcare Clinical Data, Inc, North Miami, Florida, United States
🇺🇸Harborview ID Research Clinic, Seattle, Washington, United States
🇺🇸SUNY Downstate Medical Center, Brooklyn, New York, United States
Reduction of EArly mortaLITY in HIV-infected Adults and Children Starting Antiretroviral Therapy
- First Posted Date
- 2013-04-05
- Last Posted Date
- 2016-04-20
- Lead Sponsor
- Anna Griffiths, MRC
- Target Recruit Count
- 1805
- Registration Number
- NCT01825031
- Locations
- 🇺🇬
Joint Clinical Research Centre, Mbale, Mbale, Uganda
🇰🇪Moi University Clinical Research Centre, Eldoret, Kenya
🇰🇪KEMRI Wellcome Trust Research Programme, Kilifi, Kenya
The Study Of Fluconazole For Vulvovaginal Candidiasis
- First Posted Date
- 2013-03-07
- Last Posted Date
- 2021-07-19
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 157
- Registration Number
- NCT01806623
- Locations
- 🇯🇵
Hayakawa Clinic, Osaka, Japan
🇯🇵Mori Ladies Clinic, Fukuoka, Japan
🇯🇵IZUMI Ladies' Clinic, Gifu, Japan
A Drug-Drug Interaction Study of the Effect of Rabeprazole, Itraconazole or Fluconazole on the Pharmacokinetics of Vismodegib
- Conditions
- Interventions
- First Posted Date
- 2013-01-21
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Genentech, Inc.
- Target Recruit Count
- 92
- Registration Number
- NCT01772290
Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa
- Conditions
- Interventions
- First Posted Date
- 2012-10-29
- Last Posted Date
- 2016-07-12
- Lead Sponsor
- ANRS, Emerging Infectious Diseases
- Target Recruit Count
- 41
- Registration Number
- NCT01715922
- Locations
- 🇧🇮
Hôpital général, Muyinga, Burundi
🇨🇮Service de Maladies Infectieuses & Tropicales - Hôpital Triechville, Abidjan, Côte D'Ivoire
🇧🇮CHU Kamenge, Bujumbura, Burundi
Drug Development Updates
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