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Nevirapine

Generic Name
Nevirapine
Brand Names
Viramune
Drug Type
Small Molecule
Chemical Formula
C15H14N4O
CAS Number
129618-40-2
Unique Ingredient Identifier
99DK7FVK1H
Background

A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.

Indication

For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Associated Therapies
-

A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT00000896
Locations
🇺🇸

Ucsd, Avrc Crs, San Diego, California, United States

🇺🇸

University of Colorado Hospital CRS, Aurora, Colorado, United States

🇺🇸

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis, Indiana, United States

A Study of Nevirapine to Prevent HIV Transmission From Mothers to Their Infants

Phase 3
Completed
Conditions
HIV Infections
Pregnancy
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
2009
Registration Number
NCT00001135
Locations
🇺🇸

Children's Hosp of Boston, Boston, Massachusetts, United States

🇺🇸

Univ of Miami (Pediatric), Miami, Florida, United States

🇺🇸

Duke Univ Med Ctr, Durham, North Carolina, United States

and more 17 locations

Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection

Phase 1
Completed
Conditions
HIV Infection
First Posted Date
1999-11-04
Last Posted Date
2017-07-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
42
Registration Number
NCT00001644
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

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