Nevirapine
- Generic Name
- Nevirapine
- Brand Names
- Viramune
- Drug Type
- Small Molecule
- Chemical Formula
- C15H14N4O
- CAS Number
- 129618-40-2
- Unique Ingredient Identifier
- 99DK7FVK1H
- Background
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
- Indication
For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.
- Associated Conditions
- Human Immunodeficiency Virus Type 1 (HIV-1) Infection
- Associated Therapies
- -
Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study)
- Conditions
- Interventions
- First Posted Date
- 2012-07-11
- Last Posted Date
- 2017-10-27
- Lead Sponsor
- University of Cape Town
- Target Recruit Count
- 200
- Registration Number
- NCT01637558
- Locations
- 🇿🇦
Desmond Tutu Centre, Cape Town, Western Cape, South Africa
🇿🇦KIDCRU, Tygerberg Hospital, Department of Paediatrics and Child Health, Stellenbosch University, South Africa., Cape Town, Western Cape, South Africa
🇲🇼Queen Elizabeth Central Hospital, Blantyre, Malawi
Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected
- First Posted Date
- 2012-07-03
- Last Posted Date
- 2019-08-06
- Target Recruit Count
- 52
- Registration Number
- NCT01632891
- Locations
- 🇰🇪
AMPATH at Moi Univ. Teaching Hosp. Eldoret CRS (12601), Eldoret, Kenya
🇰🇪Walter Reed Project - Kenya Med. Research Institute Kericho CRS (12501), Kericho, Kenya
🇲🇼College of Med. JHU CRS (30301), Blantyre, Malawi
Pharmacokinetic Evaluation of Changes in Nevirapine AUC Due to Differences in Weight
- First Posted Date
- 2011-04-14
- Last Posted Date
- 2011-04-14
- Lead Sponsor
- Western University of Health Sciences
- Target Recruit Count
- 21
- Registration Number
- NCT01335360
- Locations
- 🇺🇸
Jeffrey Goodman Clinic, Los Angeles, California, United States
Influence of Nevirapine on HCV Viral Load
- Conditions
- Interventions
- First Posted Date
- 2011-01-17
- Last Posted Date
- 2011-01-17
- Lead Sponsor
- Valme University Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT01277627
- Locations
- 🇪🇸
Valme University Hospital, Seville, Spain
Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART
- Conditions
- Interventions
- First Posted Date
- 2008-07-21
- Last Posted Date
- 2016-09-19
- Target Recruit Count
- 105
- Registration Number
- NCT00719602
- Locations
- 🇿🇲
George Clinic CRS (30273), Lusaka, Zambia
🇺🇬Makerere University - JHU Research Collaboration (30293), Kampala, Uganda
🇲🇼University of North Carolina Lilongwe (12001), Lilongwe, Malawi
VENICE Study Nevirapine Full Dose/Dose Escalation
- First Posted Date
- 2008-06-24
- Last Posted Date
- 2009-02-11
- Lead Sponsor
- Clinical Trial Agency of HIV Study Group
- Target Recruit Count
- 80
- Registration Number
- NCT00704249
- Locations
- 🇪🇸
Hospital Provincial Reina Sofía de Córdoba, Cordoba, Spain
🇪🇸Hospital Gregorio Marañón, Madrid, Spain
🇪🇸Hospital Ramón y Cajal, Madrid, Spain
Durability of Nevirapine-Based Antiretroviral Regimen
- Conditions
- First Posted Date
- 2008-06-24
- Last Posted Date
- 2008-07-08
- Lead Sponsor
- Bamrasnaradura Infectious Diseases Institute
- Target Recruit Count
- 140
- Registration Number
- NCT00703898
- Locations
- 🇹🇭
Department of Medicine, Bamrasnaradura Infectious Diseases Institute, Nonthaburi, Thailand
Safety and Pharmacokinetic Study of Fixed Dose Combination of Zidovudine, Lamivudine, and Nevirapine in HIV-Infected Children in Thailand
- Conditions
- Interventions
- First Posted Date
- 2008-05-06
- Last Posted Date
- 2021-11-09
- Target Recruit Count
- 42
- Registration Number
- NCT00672412
- Locations
- 🇹🇭
Prapokklao Hosp. CRS, Muang District, Chantaburi, Thailand
🇹🇭Siriraj Hospital Mahidol University CRS, Bangkok, Ratchathewi, Thailand
🇹🇭Chonburi Hosp. CRS, Chonburi, Thailand
Trial About Hepatic Security of Antiretroviral Treatment Based on Kaletra Versus Nevirapine in Co-infected HIV/HCV Patients
- First Posted Date
- 2008-04-18
- Last Posted Date
- 2019-12-05
- Lead Sponsor
- Germans Trias i Pujol Hospital
- Target Recruit Count
- 9
- Registration Number
- NCT00661349
- Locations
- 🇪🇸
Hospital General Universitario de Alicante, Alicante, Spain
🇪🇸Hospital Clínico de Salamanca, Salamanca, Spain
🇪🇸Hospital Universitario Príncipe de Asturias, Madrid, Spain
Nevirapine Study for the Prevention of Maternal-Infant HIV Transmission in Uganda
- Conditions
- Interventions
- First Posted Date
- 2008-03-20
- Last Posted Date
- 2008-04-02
- Target Recruit Count
- 722
- Registration Number
- NCT00639938
Drug Development Updates
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