Huperzine A

Generic Name
Huperzine A
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C15H18N2O
CAS Number
102518-79-6
Unique Ingredient Identifier
0111871I23
Background

Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss Huperzia serrata. The botanical has been used in China for centuries for the treatment of swelling, fever and blood disorders. Recently in clinical trials in China, it has demonstrated neuroprotective effects. It is currently being investigated as a possible tre...

Indication

Investigated for use/treatment in alzheimer's disease.

Associated Conditions
-
Associated Therapies
-

Early Diagnosis and Early Treatment of Alzheimer's Disease Based on Senile Plaque Imaging

First Posted Date
2016-10-12
Last Posted Date
2019-04-16
Lead Sponsor
Shanghai Mental Health Center
Target Recruit Count
300
Registration Number
NCT02931136
Locations
🇨🇳

Shanghai Mental Health Center, Shanghai, Shanghai, China

Effects of Huperzine A in Treatment of Moderate to Severe TBI

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2012-08-30
Last Posted Date
2019-11-05
Lead Sponsor
Spaulding Rehabilitation Hospital
Target Recruit Count
14
Registration Number
NCT01676311
Locations
🇺🇸

Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, United States

Study of Huperzine A Sustained-Release Tablets in Patients With Alzheimer's Disease

First Posted Date
2011-01-25
Last Posted Date
2011-01-25
Lead Sponsor
Shandong Luye Pharmaceutical Co., Ltd.
Target Recruit Count
390
Registration Number
NCT01282619
Locations
🇨🇳

Shanghai Mental Health Center, Shanghai, Shanghai, China

Evaluation of Three Potential Central Nervous System (CNS) Pretreatments for Soman Exposure on Human Performance

First Posted Date
2010-09-03
Last Posted Date
2017-05-03
Lead Sponsor
U.S. Army Medical Research and Development Command
Target Recruit Count
84
Registration Number
NCT01194336
Locations
🇺🇸

Walter Reed Army Institute of Research, Silver Spring, Maryland, United States

Comparative Bioavailability Study of an Immediate Release and Controlled Release Oral Formulations of Huperzine A

Not Applicable
Conditions
Interventions
First Posted Date
2010-06-03
Last Posted Date
2010-06-03
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
8
Registration Number
NCT01136551
Locations
🇮🇱

Hadassah University Hospital, Jerusalem, Israel

Huperzine-A to Help With Mental Problems and the Inability to Care for Onself in Patients With Schizophrenia

Phase 4
Conditions
Interventions
First Posted Date
2009-11-13
Last Posted Date
2009-11-13
Lead Sponsor
VA Nebraska Western Iowa Health Care System
Target Recruit Count
15
Registration Number
NCT01012830
Locations
🇺🇸

Veterans Affairs Nebraska Western Iowa Health Care System, Omaha, Nebraska, United States

Huperzine A in Alzheimer's Disease

Phase 2
Completed
Conditions
First Posted Date
2004-05-27
Last Posted Date
2008-02-21
Lead Sponsor
National Institute on Aging (NIA)
Target Recruit Count
150
Registration Number
NCT00083590
Locations
🇺🇸

University of California, Irvine, Irvine, California, United States

🇺🇸

Premiere Research Institute, West Palm Beach, Florida, United States

🇺🇸

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States

and more 26 locations
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