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Dolasetron

Generic Name
Dolasetron
Brand Names
Anzemet
Drug Type
Small Molecule
Chemical Formula
C19H20N2O3
CAS Number
115956-12-2
Unique Ingredient Identifier
82WI2L7Q6E

Overview

Dolasetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative nausea and vomiting. Dolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist. This drug is not shown to have activity at other known serotonin receptors, and has low affinity for dopamine receptors.

Background

Dolasetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative nausea and vomiting. Dolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist. This drug is not shown to have activity at other known serotonin receptors, and has low affinity for dopamine receptors.

Indication

For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including initial and repeat courses of chemotherapy. Also used for the prevention of postoperative nausea and vomiting. This drug can be used intravenously for the treatment of postoperative nausea and vomiting.

Associated Conditions

  • Chemotherapy-Induced Nausea and Vomiting
  • Post Operative Nausea and Vomiting (PONV)

FDA Approved Products

ANZEMET
Manufacturer:Validus Pharmaceuticals LLC
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/12/08
NDC:30698-220

Singapore Approved Products

No Singapore products found for this drug

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