Quetiapine

Generic Name
Quetiapine
Brand Names
Seroquel
Drug Type
Small Molecule
Chemical Formula
C21H25N3O2S
CAS Number
111974-69-7
Unique Ingredient Identifier
BGL0JSY5SI
Background

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivi...

Indication

Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in comb...

Associated Conditions
Bipolar 1 Disorder, Depressive Episodes, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
Associated Therapies
-
Clinical Trials
Related News

Clinical Effectiveness of Newer Antipsychotics in Comparison With Conventional Antipsychotics in Schizophrenia

First Posted Date
2010-07-16
Last Posted Date
2015-06-22
Lead Sponsor
University of Bremen
Target Recruit Count
149
Registration Number
NCT01164059
Locations
🇩🇪

Klinikum Bremen-Ost gGmbH, Bremen, Germany

🇩🇪

Rheinische Kliniken Düsseldorf der Heinrich-Heine-Universität, Düsseldorf, Germany

🇩🇪

Privat-Nerven-Klinik Dr. med. Kurt Fontheim, Liebenburg, Germany

and more 15 locations

15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated

First Posted Date
2010-07-07
Last Posted Date
2015-04-24
Lead Sponsor
Janssen Scientific Affairs, LLC
Target Recruit Count
450
Registration Number
NCT01157351

A Long-Term, Open-Label, Study on Schizophrenia

First Posted Date
2010-05-25
Last Posted Date
2013-01-21
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1210
Registration Number
NCT01129674
Locations
🇺🇦

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Vinnytsya, Ukraine

Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis

Phase 4
Conditions
Psychosis
Interventions
Drug: Quetiapine
Drug: Aripiprazole
First Posted Date
2010-05-07
Last Posted Date
2014-10-03
Lead Sponsor
Anne Katrine Pagsberg
Target Recruit Count
300
Registration Number
NCT01119014
Locations
🇩🇰

Aalborg Psychiatric Hospital, Aalborg, Denmark

🇩🇰

Psychiatric Centre Copenhagen, Rigshospitalet, Copenhagen, Denmark

🇩🇰

Hillerød Hospital, Hillerød, Denmark

and more 6 locations

Post-Traumatic Stress Disorder (PTSD) and Seroquel

Not Applicable
Completed
Conditions
Post-Traumatic Stress Disorder
Interventions
Drug: Seroquel
First Posted Date
2010-02-10
Last Posted Date
2017-05-30
Lead Sponsor
Cambridge Health Alliance
Target Recruit Count
34
Registration Number
NCT01066156
Locations
🇺🇸

Central Street Health Center, Somerville, Massachusetts, United States

Efficacy and Safety of Utapine vs. Seroquel in Patients With Bipolar Mania

First Posted Date
2010-01-07
Last Posted Date
2010-01-15
Lead Sponsor
Taichung Veterans General Hospital
Target Recruit Count
40
Registration Number
NCT01043679
Locations
🇨🇳

Taichung Veterans General Hospital, Taichung City, Taiwan

Quetiapine (Seroquel XR) for the Treatment of Fibromyalgia: a Clinical and Mechanistic Pilot Study

Phase 4
Completed
Conditions
Fibromyalgia
Interventions
Drug: placebo
Drug: quetiapine
First Posted Date
2009-09-24
Last Posted Date
2011-10-05
Lead Sponsor
Université de Sherbrooke
Target Recruit Count
52
Registration Number
NCT00983320
Locations
🇨🇦

University of Sherbrooke, Sherbrooke, Quebec, Canada

Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms

First Posted Date
2009-08-10
Last Posted Date
2017-04-20
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
32
Registration Number
NCT00955474
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

A Double-blind, Randomized, Controlled Trial of Quetiapine Versus Haloperidol for the Treatment of Delirium

Phase 3
Terminated
Conditions
Delirium
Interventions
Drug: quetiapine
Drug: haloperidol
First Posted Date
2009-08-07
Last Posted Date
2011-06-23
Lead Sponsor
Chiang Mai University
Target Recruit Count
52
Registration Number
NCT00954603
Locations
🇹🇭

Department of psychiatry, faculty of medicine, Chiang Mai university, Chiang Mai, Thailand

Study of Quetiapine Treatment for Cannabis Dependence

Phase 2
Completed
Conditions
Cannabis Dependence
Interventions
Drug: quetiapine
First Posted Date
2009-08-07
Last Posted Date
2019-04-24
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
15
Registration Number
NCT00954681
Locations
🇺🇸

Substance Treatment Research Service (STARS) of Columbia University, New York, New York, United States

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