Overview
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Indication
EPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2024/11/29 | Phase 3 | Not yet recruiting | |||
2024/07/10 | Early Phase 1 | Not yet recruiting | |||
2020/12/24 | N/A | Completed | |||
2020/09/24 | Phase 4 | Completed | |||
2020/07/07 | Phase 3 | Completed | Estudios Clínicos Latino América | ||
2020/01/09 | Phase 3 | Completed | Mochida Pharmaceutical Company, Ltd. | ||
2019/07/05 | Phase 1 | Terminated | |||
2019/03/21 | Phase 1 | Completed | |||
2018/10/02 | Phase 3 | Completed | Mochida Pharmaceutical Company, Ltd. | ||
2018/09/05 | Phase 4 | UNKNOWN |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Avion Pharmaceuticals, LLC | 75854-313 | ORAL | 40 mg in 1 1 | 1/7/2021 | |
| PBM Pharmaceuticals, Inc | 66213-543 | ORAL | 35 mg in 1 1 | 2/6/2013 | |
| Acella Pharmaceuticals, LLC | 42192-301 | ORAL | 35 mg in 1 1 | 10/11/2023 | |
| CarWin Pharmaceutical Associates, LLC | 15370-250 | ORAL | 15 mg in 1 1 | 12/23/2019 | |
| Acella Pharmaceuticals, LLC | 42192-332 | ORAL | 40 mg in 1 1 | 6/27/2019 | |
| PBM Pharmaceuticals, Inc | 66213-542 | ORAL | 35 mg in 1 1 | 5/23/2011 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| DANES MAXEPA/EVENING PRIMROSE OIL capsule | 50728 | Danes Pty Ltd | Medicine | A | 11/3/1994 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| HERBALIFELINE | herbalife international of luxembourg s à r l | 02248423 | Capsule - Oral | 119 MG | 7/19/2004 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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