Cefiderocol

Generic Name
Cefiderocol
Brand Names
Fetroja, Fetcroja
Drug Type
Small Molecule
Chemical Formula
C30H34ClN7O10S2
CAS Number
1225208-94-5
Unique Ingredient Identifier
SZ34OMG6E8
Background

Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam antibiotics. Unlike other agents in this category, cefiderocol is a siderophore able to undergo active transport into the bacterial cell through iron channels. It represents a significant addition to antibacterial treatment option as it has proven to ...

Indication

Cefiderocol is indicated for the treatment of complicated urinary tract infections with or without pyelonephritis.

Associated Conditions
Complicated Urinary Tract Infection, Nosocomial Pneumonia, Pyelonephritis, Ventilator Associated Bacterial Pneumonia (VABP)
Associated Therapies
-
shionogi.com
·

IDWeek 2024: Shionogi Presents Largest Global Real-World Evidence Study of Cefiderocol

Fetroja® (cefiderocol) treats cUTIs and HABP/VABP in adults caused by specific Gram-negative bacteria. It is contraindicated in severe hypersensitivity to cefiderocol or other beta-lactam drugs. Fetroja may increase mortality in carbapenem-resistant infections and cause hypersensitivity reactions, CDAD, seizures, and CNS adverse reactions. It should be used to treat proven or strongly suspected bacterial infections to prevent drug resistance.
© Copyright 2024. All Rights Reserved by MedPath