MedPath

Glucose

Generic Name
Glucose
Brand Names
Bss Ophthalmic Solution, Citrasate, Clinimix 2.75/5, Clinimix E 2.75/5, Dextroject, Dianeal, H.E.L.P.bicel, Hemosate Ultra, Lactate 1-2-3, Leukotrap, Naturalyte, Nauzene, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Physioneal 40, Sag-M, Sclerodex, Selectbag One
Drug Type
Small Molecule
Unique Ingredient Identifier
IY9XDZ35W2

Overview

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Background

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Indication

Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions

  • Arrhythmia
  • Caloric Deficit
  • Edema of the cerebrum
  • Hypoglycemia
  • Metabolic Alkalosis

Clinical Trials

FDA Approved Products

POTASSIUM CHLORIDE IN DEXTROSE
Manufacturer:B. Braun Medical Inc.
Route:INTRAVENOUS
Strength:5 g in 100 mL
Approved: 2018/09/17
NDC:0264-7625
POTASSIUM CHLORIDE IN DEXTROSE
Manufacturer:B. Braun Medical Inc.
Route:INTRAVENOUS
Strength:5 g in 100 mL
Approved: 2018/09/17
NDC:0264-7628
Dextrose
Manufacturer:Henry Schein, Inc.
Route:INTRAVENOUS
Strength:25 g in 50 mL
Approved: 2022/01/09
NDC:0404-9846
ACD-A
Manufacturer:Fenwal, Inc.
Route:INTRAVENOUS
Strength:12.25 g in 500 mL
Approved: 2022/02/11
NDC:0942-0641
DIANEAL Low Calcium with Dextrose
Manufacturer:Baxter Healthcare Corporation
Route:INTRAPERITONEAL
Strength:1.5 g in 100 mL
Approved: 2019/11/21
NDC:0941-0424

Singapore Approved Products

No Singapore products found for this drug

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