Octreotide

Generic Name
Octreotide
Brand Names
Bynfezia, Mycapssa, Sandostatin
Drug Type
Biotech
Chemical Formula
-
CAS Number
83150-76-9
Unique Ingredient Identifier
RWM8CCW8GP
Background

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is a life-threat...

Indication

Octreotide by injection is used for the treatment of acromegaly and the reduction of flushing and diarrhea symptoms related to carcinoid tumors and/or vasoactive intestinal peptide (VIPoma) tumors. The delayed-release oral formulation is used for the long-term treatment of acromegaly in patients who tolerate and respond adequately to injectable octreotide an...

Associated Conditions
Acromegaly, Diarrhea, Metastatic Carcinoid Tumors
Associated Therapies
Long-term maintenance therapy

Outcome of ADPKD With Octreotide LAR

First Posted Date
2024-01-05
Last Posted Date
2024-03-15
Lead Sponsor
Mario Negri Institute for Pharmacological Research
Target Recruit Count
70
Registration Number
NCT06193616
Locations
🇮🇹

ASST HPG23 - Unità di Nefrologia, Bergamo, BG, Italy

Efficacy and Safety of Octreotide in Laparoscopic Hepatectomy Surgery: Effect on Blood Loss, Need for Vasoactive Drugs, Transfusion Requirements.

First Posted Date
2023-10-17
Last Posted Date
2023-10-17
Lead Sponsor
Clinica Universidad de Navarra, Universidad de Navarra
Target Recruit Count
62
Registration Number
NCT06085976
Locations
🇪🇸

Clinica Universidad de Navarra, Pamplona, Spain

Comparison of 2 Days Versus 5 Days of Octreotide After Endoscopic Therapy in Preventing Early Esophageal Varices Rebleed : A Randomized Controlled Study

Phase 4
Conditions
Interventions
First Posted Date
2022-01-20
Last Posted Date
2022-05-18
Lead Sponsor
Tanta University
Target Recruit Count
184
Registration Number
NCT05199038

Hemodynamic Profile of Terlipressin and Octreotide in Patients With Cirrhosis and Portal Hypertension. A Randomised, Single Blinded Clinical Trial.

First Posted Date
2020-04-20
Last Posted Date
2020-04-20
Lead Sponsor
Juan A. Arnaiz
Target Recruit Count
36
Registration Number
NCT04353193
Locations
🇪🇸

Hospital Clinic, Barcelona, Spain

Sandostatin (Octreotide LAR) May Lead to Clinical Improvement Through Receptor Occupation Optimisation

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2019-10-25
Last Posted Date
2019-10-25
Lead Sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Target Recruit Count
10
Registration Number
NCT04140409

Angiotensin 2 for Hepatorenal Syndrome

First Posted Date
2019-08-07
Last Posted Date
2024-03-06
Lead Sponsor
University of California, Los Angeles
Registration Number
NCT04048707

Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903)

First Posted Date
2019-07-22
Last Posted Date
2021-08-17
Lead Sponsor
Nanfang Hospital, Southern Medical University
Target Recruit Count
60
Registration Number
NCT04028323
Locations
🇨🇳

The First Hospital of Lanzhou University, Lanzhou, Gansu, China

🇨🇳

The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

🇨🇳

Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China

and more 7 locations

Palliative Management of Inoperable Malignant Bowel Obstruction

First Posted Date
2019-07-22
Last Posted Date
2022-11-29
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
15
Registration Number
NCT04027348
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

Terlipressin on Effect of Renal Function in Cirrhotic Patients With Acute Gastrointestinal Hemorrhage

First Posted Date
2019-02-19
Last Posted Date
2019-07-05
Lead Sponsor
General Hospital of Shenyang Military Region
Target Recruit Count
1682
Registration Number
NCT03846180
Locations
🇨🇳

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

🇨🇳

Department of Gastroenterology, Air Force Hospital of Northern Theater Command, Shenyang, Liaoning, China

🇨🇳

Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China

and more 11 locations
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