Octreotide

Generic Name
Octreotide
Brand Names
Bynfezia, Mycapssa, Sandostatin
Drug Type
Biotech
Chemical Formula
-
CAS Number
83150-76-9
Unique Ingredient Identifier
RWM8CCW8GP
Background

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is a life-threat...

Indication

Octreotide by injection is used for the treatment of acromegaly and the reduction of flushing and diarrhea symptoms related to carcinoid tumors and/or vasoactive intestinal peptide (VIPoma) tumors. The delayed-release oral formulation is used for the long-term treatment of acromegaly in patients who tolerate and respond adequately to injectable octreotide an...

Associated Conditions
Acromegaly, Diarrhea, Metastatic Carcinoid Tumors
Associated Therapies
Long-term maintenance therapy

Etiology, Assessment and Treatment of Post-gastric Bypass Severe Hypoglycemia

First Posted Date
2013-05-31
Last Posted Date
2019-10-28
Lead Sponsor
University of Aarhus
Target Recruit Count
33
Registration Number
NCT01865760
Locations
🇩🇰

Department of Endocrinology, Aarhus University Hospital, Aarhus C, Denmark

Ghrelin Suppression by Octreotide in Prader-Willi

Not Applicable
Active, not recruiting
Conditions
Interventions
First Posted Date
2012-06-07
Last Posted Date
2022-12-16
Lead Sponsor
Oregon Health and Science University
Target Recruit Count
2
Registration Number
NCT01613495

Midodrine, Octreotide and Albumin: Impact on Renal Function of Patients With Liver Cirrhosis and Renal Failure

First Posted Date
2012-04-30
Last Posted Date
2019-02-15
Lead Sponsor
Anna Cruceta
Registration Number
NCT01587222
Locations
🇪🇸

Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

Autologous Fibrin Glues for Fistulas Closure

First Posted Date
2012-03-22
Last Posted Date
2013-02-26
Lead Sponsor
Jinling Hospital, China
Target Recruit Count
122
Registration Number
NCT01561066
Locations
🇨🇳

Department of Surgery, Jinling Hospital, Nanjing, Jiangsu, China

Long-term Safety and Efficacy Study of Octreotide Implant in Patients With Acromegaly

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2011-02-14
Last Posted Date
2013-09-20
Lead Sponsor
Endo Pharmaceuticals
Target Recruit Count
12
Registration Number
NCT01295060

Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding

First Posted Date
2009-08-26
Last Posted Date
2018-03-19
Lead Sponsor
Korea University
Target Recruit Count
1034
Registration Number
NCT00966355
Locations
🇰🇷

Korea University Anam Hospital, Seoul, Korea, Republic of

Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2009-04-21
Last Posted Date
2013-09-20
Lead Sponsor
Endo Pharmaceuticals
Target Recruit Count
10
Registration Number
NCT00884715

Efficacy and Safety of Pasireotide Long Acting Release vs. Octreotide Long Acting Release in Patients With Metastatic Carcinoid Disease

First Posted Date
2008-06-04
Last Posted Date
2013-07-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
186
Registration Number
NCT00690430
Locations
🇺🇸

University of Arizona / Arizona Cancer Center, Tucson, Arizona, United States

🇺🇸

Scottsdale Healthcare/TGen Clinical Research Service TGen Clinical Research Service, Scottsdale, Arizona, United States

🇺🇸

Loma Linda University Dept. of Loma Linda CancerCent, Loma Linda, California, United States

and more 8 locations

Safety and Efficacy of Pasireotide Long Acting Release (LAR) vs. Octreotide LAR in Patients With Active Acromegaly

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-01-25
Last Posted Date
2017-07-02
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
358
Registration Number
NCT00600886
Locations
🇬🇧

Novartis Investigative Site, Southampton, United Kingdom

🇺🇸

Johns Hopkins University School of Medicine Dept.ofJohnsHopkinsUniv., Baltimore, Maryland, United States

🇺🇸

University of Michigan Comprehensive Cancer Center Deptof Endocrinology&Diabetes, Ann Arbor, Michigan, United States

and more 12 locations

The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed

First Posted Date
2007-09-26
Last Posted Date
2007-12-05
Lead Sponsor
Aga Khan University
Target Recruit Count
320
Registration Number
NCT00534677
Locations
🇵🇰

The Aga Khan University Hospital, Karachi, Sindh, Pakistan

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