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Testosterone Enanthate

Generic Name
Testosterone Enanthate
Brand Names
Delatestryl, Xyosted
Drug Type
Small Molecule
Chemical Formula
C26H40O3
CAS Number
315-37-7
Unique Ingredient Identifier
7Z6522T8N9

Overview

Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. This slow release is achieved by the presence of the enanthate ester functional group attached to the testosterone molecule. This testosterone derivative was first approved on December 24, 1953. In 2017, about 6.5 million retail prescriptions for testosterone therapy were filled . The majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products. As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.'s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector . As the first subcutaneous autoinjector product designed for testosterone replacement therapy, this innovative formulation removes transfer concerns commonly associated with testosterone gels and potentially reduces the need for in-office/in-clinic injection procedures that may inconvenience patients with frequent visits to the clinic .

Background

Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. This slow release is achieved by the presence of the enanthate ester functional group attached to the testosterone molecule. This testosterone derivative was first approved on December 24, 1953. In 2017, about 6.5 million retail prescriptions for testosterone therapy were filled . The majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products. As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.'s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector . As the first subcutaneous autoinjector product designed for testosterone replacement therapy, this innovative formulation removes transfer concerns commonly associated with testosterone gels and potentially reduces the need for in-office/in-clinic injection procedures that may inconvenience patients with frequent visits to the clinic .

Indication

⑴男性性功能低减替代疗法;⑵绝经后女性晚期乳腺癌姑息性治疗;⑶男性青春期发育迟缓。⑷再生障碍性贫血。

Associated Conditions

  • Congenital Hypogonadotropic Hypogonadism
  • Hypergonadotropic Hypogonadism
  • Idiopathic Hypogonadotropic Hypogonadism

FDA Approved Products

TESTOSTERONE ENANTHATE
Manufacturer:Eugia US LLC
Route:INTRAMUSCULAR
Strength:200 mg in 1 mL
Approved: 2018/09/19
NDC:55150-336
XYOSTED
Manufacturer:Antares Pharma, Inc.
Route:SUBCUTANEOUS
Strength:50 mg in 0.5 mL
Approved: 2023/08/01
NDC:54436-250
TESTOSTERONE ENANTHATE
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:INTRAMUSCULAR
Strength:200 mg in 1 mL
Approved: 2021/11/12
NDC:0143-9750
XYOSTED
Manufacturer:Antares Pharma, Inc.
Route:SUBCUTANEOUS
Strength:75 mg in 0.5 mL
Approved: 2023/08/01
NDC:54436-275
XYOSTED
Manufacturer:Antares Pharma, Inc.
Route:SUBCUTANEOUS
Strength:100 mg in 0.5 mL
Approved: 2023/08/01
NDC:54436-200

Singapore Approved Products

No Singapore products found for this drug

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