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Resiniferatoxin

Generic Name
Resiniferatoxin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C37H40O9
CAS Number
57444-62-9
Unique Ingredient Identifier
A5O6P1UL4I
Background

Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission of physiological pain).

Indication

Investigated for use/treatment in interstitial cystitis and urinary incontinence.

Associated Conditions
-
Associated Therapies
-
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First participants enrolled in first-in-human Phase I clinical trial with nociceptin (NOP) receptor agonist

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Grünenthal appoints Dr. Jan Adams as Chief Commercial Officer

Grünenthal's resiniferatoxin receives Breakthrough Therapy Designation from U.S. FDA for pain associated with osteoarthritis of the knee. The non-opioid therapy is in Phase III development.
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