Stavudine

Generic Name
Stavudine
Brand Names
Zerit
Drug Type
Small Molecule
Chemical Formula
C10H12N2O4
CAS Number
3056-17-5
Unique Ingredient Identifier
BO9LE4QFZF
Background

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

Indication

For the treatment of human immunovirus (HIV) infections.

Associated Conditions
Human Immunodeficiency Virus (HIV) Infections
Associated Therapies
-

Dose Optimisation of Stavudine for the Treatment of HIV Infection

First Posted Date
2016-02-02
Last Posted Date
2016-02-02
Lead Sponsor
Willem Daniel Francois Venter
Target Recruit Count
1077
Registration Number
NCT02670772
Locations
🇿🇦

Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng, South Africa

🇺🇬

The Infectious Disease Institute (IDI), Mulago Hospital Complex, Kampala, Uganda

🇮🇳

VHS-YRG Care Medical Centre, Chennai, Tamil Nadu, India

Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients

First Posted Date
2012-05-18
Last Posted Date
2012-05-18
Lead Sponsor
University of Witwatersrand, South Africa
Target Recruit Count
60
Registration Number
NCT01601899
Locations
🇿🇦

Themba Lethu Clinic, Helen Joseph Hospital, Auckland Park, Johannesburg, Gauteng, South Africa

Safety and Efficacy of Switching From Stavudine or Zidovudine to Tenofovir DF in HIV-1 Infected Children

First Posted Date
2007-09-14
Last Posted Date
2018-03-14
Lead Sponsor
Gilead Sciences
Target Recruit Count
97
Registration Number
NCT00528957
Locations
🇵🇦

Hospital del Nino, Panama City, Panama

🇺🇸

St. Jude Children's Research Hospital, Memphis, Tennessee, United States

🇺🇸

Children's Diagnostic and Treatment Center, Inc, Fort Lauderdale, Florida, United States

and more 6 locations

Antiretroviral Therapy for Advanced HIV Disease in South Africa

First Posted Date
2006-06-21
Last Posted Date
2013-05-21
Lead Sponsor
National Institutes of Health Clinical Center (CC)
Target Recruit Count
1771
Registration Number
NCT00342355
Locations
🇿🇦

Mtubatuba SIckbay, Kwazulu-Natal, South Africa

🇿🇦

Umtata Sickbay, Eastaern Cape, South Africa

🇿🇦

South African Military Health Services (SAMHS), Centurion, South Africa

and more 4 locations

Drug Levels of Tablet and Liquid Forms of Lamivudine, Nevirapine, and Stavudine in HIV Infected Thai Children

First Posted Date
2006-04-07
Last Posted Date
2021-11-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
44
Registration Number
NCT00312091
Locations
🇹🇭

Siriraj Hospital Mahidol University CRS, Bangkok, Ratchathewi, Thailand

🇹🇭

Chiang Mai University Pediatrics-Obstetrics CRS, Chiang Mai, Thailand

🇹🇭

Chonburi Hosp. CRS, Chonburri, Thailand

and more 1 locations

Evaluation of Viral Efficacy and Safety of a Reduced Dose of Stavudine (d4T): THE PHOENIX STUDY

Phase 4
Conditions
First Posted Date
2005-10-10
Last Posted Date
2005-10-25
Lead Sponsor
Groupe Hospitalier Pitie-Salpetriere
Target Recruit Count
57
Registration Number
NCT00235222
Locations
🇫🇷

Service de Maladies Infectieuses Hôpital Pitié-Salpêtrière, Paris, France

HIV Infection And Metabolic Abnormalities Protocol 1 (HAMA001)

First Posted Date
2005-09-19
Last Posted Date
2012-04-12
Lead Sponsor
Kirby Institute
Target Recruit Count
80
Registration Number
NCT00192660
Locations
🇦🇺

St. Vincent's Hospital, Sydney, New South Wales, Australia

2NN & CHARM Long-Term Follow-up Study

Phase 4
Completed
Conditions
First Posted Date
2005-08-09
Last Posted Date
2007-04-30
Lead Sponsor
International Antiviral Therapy Evaluation Center
Target Recruit Count
763
Registration Number
NCT00127972
Locations
🇦🇺

Holdsworth House Medical Practice, Darlinghurst, Australia

Anti-HIV Treatment Interruptions in HIV Infected Adults in South Africa

First Posted Date
2005-01-05
Last Posted Date
2014-08-27
Lead Sponsor
The Wistar Institute
Target Recruit Count
30
Registration Number
NCT00100646
Locations
🇿🇦

University of the Witwatersrand, Johannesburg, South Africa

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