Stavudine

Generic Name
Stavudine
Brand Names
Zerit
Drug Type
Small Molecule
Chemical Formula
C10H12N2O4
CAS Number
3056-17-5
Unique Ingredient Identifier
BO9LE4QFZF
Background

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

Indication

For the treatment of human immunovirus (HIV) infections.

Associated Conditions
Human Immunodeficiency Virus (HIV) Infections
Associated Therapies
-

Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV

Phase 2
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Triangle Pharmaceuticals
Target Recruit Count
100
Registration Number
NCT00017992
Locations
🇺🇸

USC School of Medicine / LA County Med Ctr, Los Angeles, California, United States

🇺🇸

Univ of Miami, Miami, Florida, United States

🇲🇽

Instituto Mexicano de Investigacion Clinica, Col Roma, Mexico

and more 11 locations

A Randomized, Placebo-Controlled Study of the Safety and Efficacy of Efavirenz, Didanosine, and Stavudine in Combination With or Without Hydroxyurea in Antiretroviral Naive or Experienced HIV-Infected Patients

Phase 3
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Northwestern University
Target Recruit Count
100
Registration Number
NCT00002230
Locations
🇺🇸

Northwestern Univ Med School, Chicago, Illinois, United States

A Study of Efavirenz in Combination With Stavudine and Didanosine

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Dupont Merck
Target Recruit Count
60
Registration Number
NCT00002225
Locations
🇺🇸

Univ of Rochester Med Ctr, Rochester, New York, United States

🇺🇸

AIDS Research Alliance - Chicago, Chicago, Illinois, United States

🇺🇸

North Shore AIDS Hosp / Division of Infectious Disease, Manhassett, New York, United States

and more 2 locations

Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With Hemophilia

Phase 4
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
55
Registration Number
NCT00002386
Locations
🇺🇸

Riley Hosp for Children, Indianapolis, Indiana, United States

🇺🇸

Georgetown U Med Ctr / Div of Hematology / Oncology, Washington, District of Columbia, United States

🇺🇸

Emory Univ, Atlanta, Georgia, United States

and more 5 locations

A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
220
Registration Number
NCT00002430
Locations
🇺🇸

Emory Univ, Atlanta, Georgia, United States

🇺🇸

Tower ID Med Associates, Los Angeles, California, United States

🇺🇸

AIDS Community Research Consortium, Redwood City, California, United States

and more 43 locations

A Study to Compare the Safety and Effectiveness of Indinavir Combined With Stavudine and Lamivudine

Phase 2
Suspended
Conditions
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
186
Registration Number
NCT00002424
Locations
🇺🇸

UCLA School of Medicine / Ctr for Research and Education, Los Angeles, California, United States

🇺🇸

Associates in Research, Fort Myers, Florida, United States

🇺🇸

Rush Presbyterian - Saint Luke's Med Ctr, Chicago, Illinois, United States

and more 13 locations

Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV Infection

Phase 3
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2012-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
1125
Registration Number
NCT00013520
Locations
🇺🇸

The Ponce de Leon Ctr. CRS, Atlanta, Georgia, United States

🇺🇸

Northwestern University CRS, Chicago, Illinois, United States

🇺🇸

St. Louis ConnectCare, Infectious Diseases Clinic, St. Louis, Missouri, United States

and more 57 locations

A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2012-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
300
Registration Number
NCT00000918
Locations
🇺🇸

UCLA CARE Ctr, Los Angeles, California, United States

🇺🇸

Univ of Miami School of Medicine, Miami, Florida, United States

🇺🇸

Cook County Hosp, Chicago, Illinois, United States

and more 36 locations

The Safety and Effects of 1592U89 Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Infants and Children

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-28
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
32
Registration Number
NCT00000865
Locations
🇺🇸

UCSD Maternal, Child, and Adolescent HIV CRS, San Diego, California, United States

🇺🇸

Usc La Nichd Crs, Los Angeles, California, United States

🇺🇸

Tulane/LSU Maternal/Child CRS, New Orleans, Louisiana, United States

and more 4 locations

A Study of Stavudine in HIV-Infected Patients Who Have Not Had Success With Other Anti-HIV Drugs

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2011-08-05
Lead Sponsor
Bristol-Myers Squibb
Registration Number
NCT00002308
Locations
🇺🇸

Bristol - Myers Squibb Co, Princeton, New Jersey, United States

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