MedPath

Nogapendekin alfa inbakicept

Generic Name
Nogapendekin alfa inbakicept

2015-10: Expanded Natural Killer Cells and Elotuzumab for High-Risk Myeloma Post- Autologous Stem Cell Transplant (ASCT)

Phase 2
Withdrawn
Conditions
Multiple Myeloma
Interventions
Procedure: Autologous Stem Cell Transplant (ASCT)
Biological: Expanded Natural Killer (ENK) Cells
First Posted Date
2016-12-28
Last Posted Date
2020-07-10
Lead Sponsor
University of Arkansas
Registration Number
NCT03003728
Locations
🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Relapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT

Phase 2
Completed
Conditions
Acute Myelogenous Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Interventions
First Posted Date
2016-12-12
Last Posted Date
2023-11-03
Lead Sponsor
Masonic Cancer Center, University of Minnesota
Target Recruit Count
20
Registration Number
NCT02989844
Locations
🇺🇸

Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States

Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation

Phase 2
Recruiting
Conditions
Acute Myeloid Leukemia
Interventions
Procedure: Leukapheresis
Procedure: Graft cell infusion
Procedure: CIML NK cell infusion
First Posted Date
2016-05-25
Last Posted Date
2025-01-15
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
60
Registration Number
NCT02782546
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

Proof of Principle Study of Pulse Dosing of IL-15 to Deplete the Reservoir in HIV Infected People

Phase 1
Completed
Conditions
Stable ART
HIV
Interventions
First Posted Date
2014-07-16
Last Posted Date
2020-01-27
Lead Sponsor
University of Minnesota
Target Recruit Count
10
Registration Number
NCT02191098
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

QUILT-3.005: A Study of ALT-803 in Patients With Relapsed or Refractory Multiple Myeloma

Phase 1
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
First Posted Date
2014-03-31
Last Posted Date
2018-01-23
Lead Sponsor
Altor BioScience
Target Recruit Count
18
Registration Number
NCT02099539
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

🇺🇸

University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota, United States

🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

and more 1 locations

A Phase 1 Study of the Clinical and Immunologic Effects of ALT-803 in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2013-09-20
Last Posted Date
2025-01-22
Lead Sponsor
Altor BioScience
Target Recruit Count
26
Registration Number
NCT01946789
Locations
🇺🇸

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States

🇺🇸

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

🇺🇸

University of Washington, Seattle Cancer Care Alliance, Seattle, Washington, United States

and more 2 locations

Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Phase 1
Terminated
Conditions
Leukemia, Myeloid, Acute
Interventions
Procedure: Leukapheresis
Biological: Cytokine-induced killer cells
Biological: IL-2
Procedure: Peripheral blood for correlative studies
Procedure: Bone marrow for correlative studies
First Posted Date
2013-07-12
Last Posted Date
2024-01-17
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
89
Registration Number
NCT01898793
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

© Copyright 2025. All Rights Reserved by MedPath