Allopurinol
- Generic Name
- Allopurinol
- Brand Names
- Aloprim, Zyloprim
- Drug Type
- Small Molecule
- Chemical Formula
- C5H4N4O
- CAS Number
- 315-30-0
- Unique Ingredient Identifier
- 63CZ7GJN5I
- Background
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals .
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- Indication
Allopurinol is indicated in :
1) the management of patients with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy).
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- Associated Conditions
- Hyperuricemia, Primary Gout, Recurrent calcium oxalate calculi, Secondary gout, Calcium oxalate calculi Renal Calculi
- Associated Therapies
- -
A Study to Assess the Safety and Pharmacokinetics of Verinurad and Allopurinol in Asian and Chinese Subjects
- Conditions
- Interventions
- First Posted Date
- 2019-02-11
- Last Posted Date
- 2019-05-13
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 6
- Registration Number
- NCT03836599
- Locations
- 🇺🇸
Research Site, Glendale, California, United States
Evaluation of a Treatment With Allopurinol in Adenylosuccinate Lyase Deficiency
- First Posted Date
- 2018-12-17
- Last Posted Date
- 2022-10-12
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 8
- Registration Number
- NCT03776656
- Locations
- 🇫🇷
Department of Pediatry. Reference centre of Hereditary diseases of the metabolism of child and adult. Necker - Enfants malades Hospital, Paris, France
🇫🇷LA PITIE-SALPETRIERE Hospital, AP-HP, Paris, France
Effect of Allopurinol or Febuxostat to Prevent Contrast Induced Acute Kidney Injury (CI-AKI)
- Conditions
- Interventions
- First Posted Date
- 2018-12-06
- Last Posted Date
- 2018-12-06
- Lead Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
- Target Recruit Count
- 558
- Registration Number
- NCT03767322
- Locations
- 🇲🇽
Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, México City, Mexico
Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery Disease
- Conditions
- Interventions
- First Posted Date
- 2018-10-09
- Last Posted Date
- 2018-11-21
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT03700645
The Effect of Antioxidants on Skin Blood Flow During Local Heating
- Conditions
- Interventions
- First Posted Date
- 2018-09-21
- Last Posted Date
- 2018-09-21
- Lead Sponsor
- The University of Texas at Arlington
- Target Recruit Count
- 44
- Registration Number
- NCT03680638
- Locations
- 🇺🇸
Engineering Research Building, Arlington, Texas, United States
The Effect of Antioxidants on Skin Blood Flow-BH4
- First Posted Date
- 2018-09-21
- Last Posted Date
- 2018-09-26
- Lead Sponsor
- The University of Texas at Arlington
- Target Recruit Count
- 16
- Registration Number
- NCT03680573
- Locations
- 🇺🇸
Engineering Research Building, Arlington, Texas, United States
Sex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric Acid
- Conditions
- Interventions
- First Posted Date
- 2018-08-28
- Last Posted Date
- 2023-07-03
- Lead Sponsor
- University of Missouri-Columbia
- Target Recruit Count
- 34
- Registration Number
- NCT03648996
- Locations
- 🇺🇸
University of Missouri, Columbia, Missouri, United States
The Percentage of Cases of Acute Treatment With Allopurinol in Gout Patients
- First Posted Date
- 2018-07-26
- Last Posted Date
- 2018-07-26
- Lead Sponsor
- Hillel Yaffe Medical Center
- Target Recruit Count
- 700
- Registration Number
- NCT03601260
- Locations
- 🇮🇱
Hillel Yaffe Medical Center, Hadera, Israel
A Trial Comparing Single Agent Melphalan to Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion
- Conditions
- Interventions
- First Posted Date
- 2018-06-27
- Last Posted Date
- 2022-06-22
- Lead Sponsor
- Swedish Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT03570983
- Locations
- 🇺🇸
Swedish Cancer Institute, Seattle, Washington, United States
Comparative Clinical Efficacy and Safety of Coded Polyherbal Medicine for the Management of Arthritis
- First Posted Date
- 2018-04-24
- Last Posted Date
- 2018-04-24
- Lead Sponsor
- Shifa Ul Mulk Memorial Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT03506919
- Locations
- 🇵🇰
clinical trial was conducted in Bahawalpur, and Rawalpindi, Bahawalpur, Punjab, Pakistan
Drug Development Updates
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